The highest grade is the uterus simplex: every trace here of the double form is lost; the fundus no longer forms an acute angle, where it bifurcates into two cornua; but is convex. We now for the first time see the divisions of the uterus into body and cervix distinctly marked.
Uterus biangularis.
The human uterus presents a similar variety of forms, as it gradually rises in the scale of development during the different periods of utero-gestation. It is at first divided into two cornua, and usually continues so to the end of the third month, or even later; the younger the embryo the longer are the cornua, and the more acute the angle which they form; but even after this angle has disappeared, the cornua continue for some time longer.
Uterus simplex.
The uterus is at first of an equal width throughout; it is perfectly smooth and not distinguished from the vagina either internally or externally by any prominence whatever. This change is first observed when the cornua disappear and leave the uterus with a simple cavity. The upper portion is proportionably smaller, the younger the embryo is. The body of the uterus gradually increases, until at the period of puberty it is no longer cylindrical, but pyriform: even in the full-grown fœtus the length of the body is not more than a fourth part of the whole uterus; from the seventh even to the thirteenth year it has only a third, nor does it reach a half until puberty has been fully attained. The os tincæ or os uteri externum first appears as a scarcely perceptible prominence projecting into the vagina; it increases gradually, in size until the latter months of gestation, when the portio vaginalis is relatively much larger than afterwards.
The parietes of the uterus are thin in proportion to the age of the embryo. They are of an equal thickness throughout at first: at the fifth month, the cervix becomes thicker than the upper parts; between five or six years of age, the uterine parietes are nearly of an equal thickness, and remain so until the period of puberty, when the body becomes somewhat thicker than the cervix.
As the function of menstruation with its various derangements will be considered among the diseases of the unimpregnated state, we proceed to consider these changes which the uterus undergoes during pregnancy as well as during and after labour: these are very remarkable both as regards its structure, form, and size.
Shortly after conception, and before we can perceive any traces of the embryo, the uterus becomes softer and somewhat larger, its blood-vessels increased in size, and the fibrous layers of which its parietes are composed looser and more or less separated. The internal surface when minutely examined has a flocculent appearance, and very quickly after conception becomes covered with a whitish paste-like substance, which is secreted from the vessels opening upon it; this pulpy effusion soon becomes firmer and more dense; it bears a strong analogy to coagulable lymph, and forms a membrane which lines the whole cavity of the uterus, and which in the course of a few weeks (from changes to be mentioned hereafter) crosses the os uteri and thus closes it. The uterine cavity in a short time becomes still farther closed by the canal of the cervix being completely sealed, as it were, by a tough plug of gelatinous matter which is secreted by the glandules of that part.