The balance of power between the sections in the Senate, which had been maintained without difficulty thus far, was seriously threatened by this Missouri question. At the beginning of the Constitutional Union seven States were clearly destined by their climate and occupation for free labour, leaving six for slave labour. The latter thus lacked two senatorial votes of equalling the North from the beginning. The admission of Vermont and Kentucky, a Northern and a Southern State, maintained the ratio. It was continued farther by the admission of Tennessee and Ohio, Louisiana and Indiana, Mississippi and Illinois. This balance had been thus far an accident, depending upon the time when a portion of land had sufficient population for statehood; but it had become such a tacit understanding, that the admission of Alabama in 1819, it was said, made the sections exactly equal in the number of Senators. At almost the same time Missouri and Maine were ready. The latter because of climate must undoubtedly be admitted as a free State. The former must be given to slavery if the balance between the two sections was to be maintained. But the extension of the line of thirty-six thirty would make Missouri a free State. The location of States heretofore admitted had been so indisputably upon the one side or the other of the slavery-freedom line that uncertainty was impossible. Missouri, as has been shown, lay right athwart the extension.

There had been comparatively little anti-slavery agitation thus far, being confined to attacks upon the slave trade and an occasional petition from the Friends; yet the sentiment that slavery was an economic evil was firmly established in the overstocked border slave States, and that it was both an economic and moral evil was believed by a growing number in the Northern States. The "Lower South," or Gulf States, were thus left as the guardians of a system which the increasing cultivation of cotton in that region made unusually profitable and, as they thought, indispensable. Missouri lay far to the north of them, but the maintenance of political power in the Union was essential to their future if they read aright the growing hostile sentiment of the North. Immediate or gradual emancipation had been provided by every old State in the North, and slavery had been prohibited by the constitutions of the new Northern States. Feeling the approval of a good conscience, it was probable that the North would eventually demand a kindred movement in the South. There is no reformer likely to be so intolerant as the one who has left off what he considers a bad habit.

The slavery system had been so thoroughly rooted in colonial times and so freely recognised and protected in the Constitution, that few as yet contemplated interfering with it in any State where it already existed. Home rule and individual rights were too sacred for that. Majority rule had not yet made sufficient headway against individualism. But the Union had a kind of prenatal control which it could exercise over States created from Territories. Here was an opportunity to exercise it. An early attempt was made in Congress on the part of those hostile to the extension of slavery to make Missouri a free State by prohibiting "the further introduction of slavery or involuntary servitude." It was met by a counter amendment from the pro-slavery people jointly admitting Maine and Missouri with no such restrictions. This would evidently throw Missouri open to slavery.

The ensuing debates in Congress, covering parts of two sessions, opened all the sectional dissensions, showed how weak were the ties of unionism thus far developed, cut sharp lines across political parties, and shifted the old East and West sectional danger to North and South. The phrase "Mason and Dixon line" was used to express the sectional demarcation, transformed to that use, it is said, by John Randolph. Recrimination and abuse were common. Northern speakers drew insulting comparisons between the population, wealth, and prosperity of the free and slave States. They attributed the difference to the blight of slavery. Southern speakers explained that slavery was a thing of which a non-resident could not judge properly; that what appeared to an outsider as a lack of prosperity was the enjoyment of life by a people not devoted to the sordid aspects of existence; that slavery was a matter for home rule and did not concern the other half of the Union. The Northern contingent replied that slavery was a menace to free labour and that their devotion to all parts of the Union, as well as their right of self-preservation, warranted their interference. Then the Southern speakers taunted them with Shays's Rebellion, the whiskey insurrection, and the Hartford Convention, as proofs of their devotion to the Union. The people of New York were reproached with wishing to deprive Southern people of their slave property, although they themselves still held more than ten thousand slaves and held them under protection of the State laws. One Southern speaker came very near the truth when he predicted that the census for 1820 would show fully twenty thousand slaves still held in bondage in the Northern States. A long discussion arose over the number of troops each section had furnished to the Revolutionary War and upon the number of distinguished men bred in each section. The Bible was quoted freely to attack or defend human bondage. Resolutions of State Legislatures added their weight to either side. Some debaters in Congress deplored the "poisoning of the national affection," seeing in it the revival of the sectional envy and dislike dormant for the past thirty years. Other hot-blooded speakers declared that this contest could be ended only by bloodshed.

Looking beneath the unfortunate sectionalism, which was to retard the growth of the Union for the coming half-century, one sees that the people faced a new question: had the United States a right to place an anti-slavery restriction on a sovereign State at the time of creating it from a Territory? The answer would greatly affect the relation of the States to the Union. Few States had been admitted without some conditions, such as the non-taxation of public lands and the perpetual freedom of navigable waters; but those were of national importance and different from slavery, which was claimed to be of local concern. In admitting Ohio, Indiana, and Illinois, formed from the North-west Territory, Congress had provided that their constitutions should not be repugnant to the Ordinance of 1787. That this did not mean a rigid adherence to the anti-slavery provision was shown by the admission of Illinois in 1818 with an apprentice system, which made slavery possible in that State for twenty-two years to come. A motion to reject the application of Illinois on this ground was overwhelmingly defeated. The States of Kentucky, Tennessee, Mississippi, and Alabama, had been created out of the indefinite territory south of the Ohio River in which Congress had pledged itself to make no law emancipating slaves. No slavery conditions were placed upon their admission, which was considered equivalent to an agreement that they were to be slave States. Louisiana was created out of the Louisiana Purchase and Arkansas made into a Territory with the same tacit permission, as has been said. Precedent consequently taught everything and nothing so far as Missouri was concerned.

The obligations of the Union toward a State were freely discussed; whether "new states may be admitted by the Congress" meant "must" be admitted. On a small scale the discussion rehearsed the Hayne-Webster debate a decade later. Occasional pleas were heard for "the old Republican doctrine which limited the general government to the expressed powers and prevented it from encroaching on the young states or on the free movement of personal property." Various phrases in the Constitution were quoted both to prove and disprove the power of Congress to prohibit slavery in a new State. "The citizens of each state shall be entitled to all privileges and immunities of citizens in the several states," it was claimed, would permit the migration of slaveholders to Missouri with their property. "The migration or importation of such persons as any of the states now existing shall think proper to admit shall not be prohibited by the Congress prior to 1808," was said to permit, conversely, such prohibition after that date. The other side claimed that the clause was intended to refer solely to slaves imported into the United States and not to interstate migration. Under the clause that the Congress shall guarantee a republican form of government to every State, the Declaration of Independence was quoted to prove that freedom is the natural condition of a republic and that slaves were held only pending their emancipation. Such sentiments drew a sharp rebuke from the opposing side. Slaves might even then be in the gallery, it was said, to overhear such revolutionary doctrine.

So persistent were members in hunting up and interpreting various phrases of the Constitution, each to suit his own views, that one disgusted Republican protested against "a species of special pleading which hunts for powers in words and sentences taken here and there from the instrument and patched together forming something like a pretext for the exercise of power palpably interdicted by the plain sense and intention of the instrument." The cry of "home rule" for the State of Missouri on the slavery question was the forerunner of "squatter sovereignty" two decades later. Calhoun's later plea that any citizen had the right to migrate to any part of the co-operative public lands and to carry with him all his property found a first hearing in this debate on the admission of Missouri.

The equilibrium maintained so carefully in the Senate had long since disappeared in the House because of the varying distribution of population. Of the 180 members who considered the Missouri question in the more popular branch, 104 came from the free States and only 76 from the slave States. The vote of 87 to 76 by which the House finally forbade slavery in the new State was indicative to some extent of this proportion, although party lines influenced a few votes. Virginia stood solidly for slavery, and New York, with one exception, against it. Of the nineteen votes from Pennsylvania, only one was cast for slavery in Missouri. Massachusetts was almost as unanimous. North and South Carolina, Georgia and Mississippi, the future champions of the system, unanimously opposed placing such restriction on the new State. The Senate, more nearly balanced, refused to agree with the restrictive vote of the House. A counter-measure was proposed by the Southern interests to admit Maine and Missouri jointly, allowing home rule to each on the slavery question. The majority in the House opposed this method of evidently opening the new State to slavery. A deadlock between the two branches was imminent.

Meanwhile a bill had appeared in the Senate to draw the dividing-line between slavery and freedom across the Louisiana Purchase along thirty-six degrees and thirty minutes north latitude, a continuation of the Kentucky-Tennessee boundary. This would make Missouri a free State. Considering the triangular shape of the purchase, with the bulk of land lying to the north of the proposed line, the division was manifestly unequal. Roughly estimated, the proportions would be about one to seven. That would mean in time fourteen Northern and two Southern Senators. It would mean seven times the chances of population for representation in the House. At last, Henry Clay, Speaker of the House, who had favoured slavery in Missouri, was able to effect a compromise whereby thirty-six degrees and thirty minutes was accepted as the dividing-line; but the State of Missouri, which lay to the north of it, was made an exception and admitted without any restriction and, consequently, open to slavery. In all the remainder of the vast tract north of the line slavery was forbidden, as it had been in the Northwest Territory.

This extension of the slavery-freedom line ran up the Mississippi from the mouth of the Ohio, passed about the State of Missouri, returned to her southern boundary, and ran thence to the summit of the Rocky Mountains. There were now twelve free and twelve slave States in the Union. The South had gained her point in throwing Missouri open to slavery and so maintaining the balance of power in the Senate. But she had paid a heavy penalty for it. That she would remain content with this unequal distribution; that the next generation would abide by the compromise when new States were created; that the free migration of the people with their property could be checked by a parallel of latitude; that the question of territorial slavery had been settled by a drawn battle, few could hope or expect.