The next day Charles handed his remarkable declaration to the German princes in which he said: 'My predecessors ... left behind them the holy Catholic rites that I should live and die therein, and so until now with God's aid I have lived as becomes a Christian emperor.... A single monk, led astray by private judgment, has set himself against the faith held by all Christians for a thousand years and more, and impudently concludes that all Christians up to now have erred. I have therefore resolved to stake upon this cause all my dominions, my friends, my body and my blood, my life and soul.... After Luther's stiff-necked reply in my presence yesterday, I now repent that I have so long delayed proceedings against him and his false doctrines. I have now resolved never again, under any circumstances, to hear him. Under protection of his safe conduct he shall be escorted home, but forbidden to preach and seduce men with his evil doctrines and incite them to rebellion....'

But Luther's brave bearing at Worms was his most heroic moment, nor was his power in Germany ever again so great as in 1521, nor was he ever again so truly the voice of the people.[72]

On April the 25th Charles ordered him to leave Worms, and next day the monk departed, escorted by twenty horsemen. A few days later an edict was published in the emperor's name, and by authority of the Diet, depriving him of all the privileges he enjoyed as a subject of the empire, forbidding any prince to harbour or protect him, and requiring all to help in seizing his person as soon as the time specified in the safe conduct had expired. In less than a fortnight he had disappeared, rescued from his adversaries by the Elector of Saxony, who kept the place of his retreat carefully concealed.

Meanwhile Francis I. had been actively engaged in sending forces against the frontiers of Belgium and Italy. Charles, through Margaret, made an appeal to the States-General convoked at Mons on February 9th, 1521. In a spirited speech she pointed out the perfidious conduct of Francis, who she declared was daily trying to induce the European powers to make war against the emperor's dominions. Amongst others she quoted his efforts to obtain support from the Kings of Denmark and Scotland, the Dukes of Savoy, Lorraine, and Ferrara, the republic, the Swiss League, and Charles of Gueldres. She then implored the assembly to grant help to protect the empire from its enemies. The people were flattered by this appeal to their patriotism, and hastened to prove that their emperor had not appealed to them in vain.

On the 5th of May 1521 the Archduke Ferdinand concluded his marriage with Princess Anne of Hungary, and Charles conferred the five duchies of Austria, Carinthia, Carniola, Styria, and Tyrol upon his brother, to which he added later the German possessions inherited from Maximilian.

On May the 29th he confirmed a secret treaty with Leo X. through Don John Manuel, his ambassador in Rome, by which the Pope and emperor agreed to join forces to expel the French out of the Milanaise, to restore Parma and Piacenza to the Church, the emperor helping the Pope to conquer Ferrara, in return for the investiture of the kingdom of Naples. This treaty was carefully concealed from De Chièvres, whose aversion to a war with France was well known. When at length he heard of it, his grief was so great at this proof of his loss of influence over his former pupil, that it is said to have shortened his days. His death at this juncture certainly hastened the war with France, though it freed Charles from an irksome subjection and greatly helped in the development of his character. From henceforth the emperor was his own master, nor was he ever again under another governor. Instead of his boyish motto—'Nondum' (not yet), his device in future was 'Plus ultra' (yet further).

The French were the first to cross the Pyrenees and begin hostilities. When Charles, who was then at Brussels, heard the news, he exclaimed: 'God be praised that it is not I who begin the war: the King of France wishes to make me greater than I am; for, in a short time, either I shall be a very poor emperor, or he will be a poor King of France.'[73]

On the 17th of July Margaret again addressed the assembled States at Ghent, for the exchequer was very low, and men and money were needed for the war. She implored them to use every effort to protect their country, and restore peace by voting the much-needed subsidies. She begged them to avert the threatening storm, and with a voice moved by emotion said: 'Because of the love and peculiar affection his Majesty bears you, being a native of these lands, born, brought up, and nourished amongst you, he is anxious to protect you from danger, and preserve you from all harm and oppression, by driving war from out of his dominions, keeping you in peace. Which things his Majesty has willingly put before you as his good and loyal subjects, because of the entire confidence he has in you, so that you may know all his affairs and understand the danger you are in, for on this depends either your safety or ruin.' She then promised 'a perpetual safety and abundance of all good things' after peace was restored, and freedom from subjection to France. She praised the fine example of Spain and Austria, who, although they hardly knew his Majesty, had nevertheless of their own accord raised superb armaments; 'and you who have his person with you ready to use his life, his goods, and all that God has given him to preserve, help, and defend you, ought not to be less generous or less courageous than others, seeing that the case touches you so closely, and with the noise of war so near, knowing the harm which may come upon you if war breaks out, and seeing that the quarrel is just, which is as true as God is, and that He will help his Majesty. And on this account you ought to take courage and show yourselves bold and fearless, and be more willing and anxious than any others, as his Majesty does not doubt you will be, and without waiting to be asked, offer liberally your persons, goods, and chattels (as you have always done in times past) to help his Majesty in this same enterprise, which is for your own and the public good.'[74]

Margaret had not miscalculated the effect of this speech on her audience. Enthusiasm and loyalty towards the emperor and herself passed all bounds and spread like wildfire throughout the Netherlands. An army of 22,000 men was quickly raised, and assembled in the outskirts of Malines. Part of these troops the emperor despatched under the Count of Nassau to subdue the inroads of Robert de la Marck, lord of Bouillon, known as the wild Boar of the Ardennes, who had been giving considerable trouble. The emperor having offended him, he left Charles's service and threw himself upon France for protection. In the heat of his resentment he had the audacity to send a herald to Worms to declare war against the emperor before the assembled Diet. To punish this insolent vassal the Count of Nassau was sent at the head of 20,000 men to invade his territories, and in a few days took every place but Sedan, and reduced De la Marck to beg for clemency. Nassau then advanced towards the borders of France, where Charles of Gueldres was ravaging the Northern provinces, and Henry d'Albret had crossed the Pyrenees and occupied Navarre.

Meanwhile a congress had been held at Calais, under Henry VIII.'s mediation, with a view to settling all differences and establishing peace. Henry gave Wolsey full powers to arrange the negotiations, but the Cardinal, anxious to please both Francis and Charles, ended by satisfying neither, and the congress broke up without any definite result. During its progress Wolsey journeyed to Bruges and had a meeting there with Charles and Margaret, the latter having come in hot haste to visit her nephew, anxious to use her influence to procure an armistice. The Cardinal was received by the emperor and his aunt with as much respect and magnificence as though he had been King of England, but instead of furthering the treaty of peace, Wolsey, in his master's name, concluded a secret alliance with the emperor against France. This treaty, which was drawn up at Bruges on August 25th, 1521, and signed by Margaret and Jean de Berghes for the emperor, and by Wolsey for the King of England, arranged a marriage between Charles and his cousin Mary Tudor (King Henry's only child and apparent heir) as soon as the princess should have completed her twelfth year; both Charles and Henry agreeing to invade France in the spring of 1523 from opposite sides, each with an army of 40,000 men—the emperor promising to visit England on his way to Spain early in the following year. It was especially stipulated that 'one month before Charles undertook the voyage he would notify the time of it to the King of England, who would then send his fleet to sea, with about 3000 armed men on board, to drive away all enemies and pirates from the Channel and English seas, so that the emperor might safely come over to Dover or Sandwich. The King of England would receive the emperor with the greatest honour and accompany him to Falmouth, whilst the English navy would escort the emperor's fleet from Zealand to Falmouth, and together remain in that port until he embarked and then accompany him to Spain.'[75]