Another mode worthy of a passing notice is one analogous to this, adopted and recommended by the eminent Dr. G. S. Hawthorne, of Liverpool, England, who observes: "Of the medicinal remedies, the chief is opium. This, I have explained, should be given in combination with medicines of a cordial, stimulating and antispasmodic character, of which the most efficient are camphor, capsicum, ether and aromatic spirits of ammonia. The following formulæ present the combination of the medicines which I would prefer:"

℞.Powdered Opium,gr. xij.
Camphor,gr. xxx.
Capsicum,gr. ix.

Spirits of wine and conserve of roses Q. S.—mix—divide into twelve pills. Each of these pills, it will be observed, contains one grain of powdered opium. These are accompanied with the following:

℞.Chloric Æther,
Aromatic Spirits Ammonia,
Camphorated Spirits,
Tincture of Capsicum.
Of each, one drachm.
Cinnamon water, two ounces—mix.

"Cholera," observes Dr. H., "presents itself in four distinct degrees of malignity. All the modifications of the disease require to be treated on the same principles, the only difference being that, in the detail, the milder forms require less powerful doses of the medicines. The mode of treating the most malignant form of the disease, will serve as a model on which all the others are to be treated. This most malignant form has, by all writers on the subject hitherto, been pronounced incurable. They say it never was cured in a single instance, and never can be cured by the power of medicine. I shall, however, point out a mode of treating it which will prove itself infallibly successful where my directions are followed with sufficient promptness, boldness and skill." In detailing the mode of procedure, the doctor observes: "Place the patient immediately in the horizontal posture in bed, and give him on the instant, as this is an extreme case, ten of the antispasmodic pills, and two ounces of the antispasmodic mixture, and wash the whole down with a glass of undiluted brandy or whisky, flavored strongly with cloves, essence of ginger, or some such warm aromatic spice. In the mean time, have him covered with an additional blanket, and let the usual means of communicating heat, such as jars or bottles of hot water, bags of hot salt or sand, hot bricks, or whatever can be most readily procured, be applied without delay to the feet and different parts of the body, so as to restore the temperature and produce perspiration as quickly as possible. As soon as the perspiration has begun to flow freely, superadded to the medicines and cordials already administered, a glass of brandy-punch should be given, the punch to be made strong and to be swallowed hot as possible. After this, no drink should be given until the perspiration has flowed freely for a few minutes. The stomach will then retain it, and the patient should be indulged freely with copious draughts of rennet whey, warm toast-water, flavored with some agreeable spice, mint, or balm-tea, or any such mild beverage. The necessity of attending to this is most important. When the discharges from the bowels cease, and when the pulse becomes full and bounding, the body is covered with a copious, warm perspiration, which will not fail to be the case under such treatment; the danger is over. The perspiration, if the patient can bear it, should be kept up for twelve hours, and may, with advantage, be continued moderately even longer. Its duration, however, must be regulated according to the strength of the patient and the state of the pulse. After the first four or six hours, more heat need not be applied than is perfectly agreeable to the feelings of the patient. It is remarkable how suddenly the precordial oppression, etc., are relieved on the breaking out of a free perspiration, and, what is of greater importance still, the vomiting, where it exists, immediately ceases." In short, all the urgent symptoms soon subside, and the patient becomes convalescent.

Such is Dr. Hawthorne's treatment, which is affirmed to have been invariably successful. It is based on the same general principle as the preceding—a prompt and diffusive stimulant. Here we might ask, What constitutes the chief reliance in the formulæ? Was it the opium that so promptly met and arrested the disease? or the combination of the other powerful stimulants with which it was united? Dr. H. places his main reliance on this drug, and yet affirms that it produced no narcotism or other sensible effect whatever, except as a diaphoretic, and even in this its influence may be questioned. The prognosis becomes favorable from the fact of a sudden rise in the temperature of the body, for the icy-coldness disappeared, the heat of the surface returned, the circulation was equalized and a profuse perspiration set in, and, as these conditions appeared, the urgent symptoms subsided. Not the excessive doses of opium, but the remedies in combination as a whole, produced by its prompt stimulating power these results, and the patient was thus relieved.

Mr. Forward, while superintending some of the public works in the State of Kentucky, in 1832, had in his employ more than two hundred laborers, among whom the Cholera Epidemic of that year appeared about a week before its irruption in Louisville. The first case was that of a young, sober, industrious white laborer, who was at the time vigorous and apparently healthy. It was a sudden and severe case and occurred about eleven o'clock at night. The physicians who usually attended these men were at a distance, and could not be obtained without considerable delay. Under these circumstances, Mr. Forward, after visiting the patient, becoming acquainted with the symptoms, and believing it a genuine case of cholera, commenced treatment at once, fearing, as he states, the patient could not live till a physician could be obtained. It was, indeed, a desperate case; violent spasms, with constant vomiting and severe purging, attended with that livid appearance and peculiar coldness so characteristic of the disease. "Of the treatment," says Mr. Forward, "I gave him first a quick, stimulating emetic prepared from the lobelia seed, which checked the vomiting and purging, but had little effect upon the spasms. I then applied the steam bath, having his feet and legs at the same time immersed in water as warm as he could bear, which was made strong with salt and wood ashes. I then sweetened a tumbler of warm water and put into it a tea-spoonful of "number six," and about the fourth part of a tea-spoonful of Cayenne pepper, and gave him one-third of it when I commenced sweating him, and the balance at intervals while he was sweating. By the time he had been sweated ten minutes, he was free from spasms and pain, but I continued the sweating ten or fifteen minutes longer, then wiped dry, after which the patient laid down and went to sleep—being thus relieved and cured."

Another case of a colored man who was strictly temperate and healthful occurred an hour or two later the same night. His attack, too, was sudden, and still more severe; cramps very violent, vomiting and purging equally as severe, though he had not been awakened from his slumbers more than fifteen minutes. This case was treated the same as the former, with the emetic, sweating, and when the sweating had subsided, administered a table-spoonful of spirits of turpentine, which relieved him entirely, and he soon went to sleep. The next morning both were comfortable, and went to work and remained well. During the prevalence of cholera at that time, Mr. Forward had thirteen cases in his own family, and, on one day when the epidemic was at its height, seven cases among the laborers. All these and many others that occurred were treated in the same manner, with the same undeviating success. Not a single instance of death from cholera in his own family, or among the hands on the road. When the epidemic cholera reappeared in 1835, the same course of treatment was pursued, with the same uniform success. Such results, considering the malignant character of the disease, are truly astonishing. Whatever may be said of the general principle of practice in these cases, its success must be admitted as equaling, if not surpassing, the treatment of any equal number of cases on record. Though conducted by an unpretending and unprofessional gentleman, yet, out of the whole number attacked during the continuance of the epidemic, not a single case was lost.

In a report of a case of cholera treated successfully by rectified oil of turpentine, administered internally as a specific, by Richard Brown, Esq., Surgeon, Cobham, Surrey, November, 1848, it is stated that the patient, "aged fourteen, having suffered from severe bowel complaint, presented all the symptoms of cholera in the stage of collapse. The bowels acted incessantly, and anything taken into the stomach was immediately rejected; the pain around the umbilicus was intense, attended with severe cramps of the legs; the pulse exceedingly small, and scarcely perceptible; tongue coated in the centre, and flabby; the surface of the body much below the natural standard; the countenance of a blue cast, and expressive of the greatest anxiety. So decided, indeed, was the symptom that the case was considered almost without hope." "But I had determined," says the physician "to treat the first case of cholera that occurred in my practice with rectified oil of turpentine, given internally, the active principle of which, camphogen, possesses stimulating, diuretic, diaphoretic, sedative, antispasmodic, antiputrescent properties. I administered immediately one drachm of it combined with mucilage and aromatics, directing it to be repeated every two hours, the patient to be kept warm and to take meal broth with excess of salt."

Now mark the result of this simple, uncombined remedy. In the evening of the same day all the urgent symptoms were assuaged, the purging and vomiting had ceased, the pulse was raised, the surface of the body had become warm and moist with perspiration, the pain around the umbilicus diminished, and the cramps less violent, but the countenance still bore the appearance of great anxiety. Such were the immediate results of the administration of this remedy, which appear, from the subsequent history of the case, to have been permanent and unattended with any constitutional derangement, or other serious and unpleasant effect. On the morning of the next day the patient was steadily improving; much of the anxiety of countenance had vanished, but the pain in the belly and cramps of the legs still remained, though much relieved. On the second morning after the attack the patient was very much better; no pain in the belly, and does not feel sick from the turpentine. On the third morning the patient was up, and, though exceedingly weak, there was no trace of any alarming symptom remaining. The bowels had moved from the effects of a previous dose of calomel (two grains) given the next morning after the attack, and the evacuation was much more healthful. A mild tonic and alterative plan of treatment was all that was necessary to restore the patient to her usual health, and she is now well. The remedy was given at first every two hours, then every four, and lastly every six hours. This treatment commenced on the 26th and terminated on the morning of the 29th. Its duration about sixty hours, when the patient is declared convalescent and comparatively well. Here we might ask, What experiment with any single remedy has been more important and satisfactory in indicating and directly pointing out a general principle of practice for the successful treatment and cure of this formidable disease? We say single remedy, for it is doubtful whether the two grains of calomel exercised any curative influence whatever, or in any way varied the result. It is, therefore, to the use of the rectified oil of turpentine that the favorable termination and cure of the disease is to be attributed.