Chaereas, the handsome young Greek hero, son of Ariston of Syracuse Callirhoe, the beautiful young Greek heroine, daughter of Hermocrates, a famous general of Syracuse Polycharmus, a young Greek, the devoted friend of Chaereas Hermocrates, the general of Syracuse Theron, a pirate Dionysius, the governor of Miletus Mithridates, satrap of Caria Artaxerxes, king of the Persians Statira, his wife, queen of the Persians Pharnaces, the governor of Lydia and Ionia Rhodogyne, the sister of Pharnaces, daughter of Zopyrus, wife of Megabyzus, a Persian beauty.

The minor characters of importance are:

Leonas, a slave-dealer of Miletus Plangon, a female slave of Dionysius Phocas, slave and overseer of Dionysius, husband of Plangon Artaxates, the eunuch of Artaxerxes Hyginus, a servant of Mithridates.

The list of characters reveals at once a connection of Chariton’s novel with the Ninus Romance because of the use of historical characters. Hermocrates, the great general of Syracuse who defeated the Athenians in the naval battle, 414 B.C., is the father of the heroine and is referred to repeatedly with the greatest pride. Artaxerxes, the king of the Persians, appears in person in courts and in wars. Historical events too are mentioned as if to give a background of reality: the contests between the Syracusans and the Athenians; the war between the Greeks and the Persians; the rebellion of Egypt against Persia; the merit of Cyrus the Great in organizing the army.

Against such a background of plausible reality, the plot develops along three main lines of interest: love, adventure and religion. The story begins with the introduction of the radiant young hero and heroine of Syracuse when they fall in love at first sight at a festival of Aphrodite. Almost immediately they are married, but their ecstatic happiness is short, for Callirhoe’s many other suitors, angry at her choice, plot revenge. They make her husband jealous by false stories of a lover whom his bride favors, and, by staging a surreptitious admission to his house of a lover of Callirhoe’s maid, convince Chaereas that his wife is faithless. In passionate fury he dashes to his wife’s room and when Callirhoe overjoyed at his unexpected return rushes to meet him, he kicks her with such violence in the middle of her body that she falls down, to all appearance dead. Chaereas is tried for murder and pleads for his own condemnation, but is acquitted against his will by the appeal of Hermocrates.

Callirhoe is now given a magnificent funeral and buried with much treasure. The heroine, however, who had only fainted, soon revives, but while she is bemoaning her sad fate, a band of pirates, led by Theron, breaks open the tomb, steals the treasure, kidnaps the girl, then sets sail with all speed for the east. At Miletus, Theron sells Callirhoe as a slave to Dionysius, a noble Ionian prince. He soon falls in love with his slave, but learning her story (except the fact that she was already married which Callirhoe omits) respects her tragic position and woos her with delicacy and consideration. Callirhoe, on finding that she is two months with child, decides to accept the advice of the maid Plangon and marry Dionysius to give her baby a father. Plangon assures Callirhoe that the child will be considered a premature seven months baby, and she secures from Dionysius a promise to bring up as his honored children any sons of the marriage. Book III tells how Chaereas found the tomb empty; how Theron was captured, forced to tell the truth by torture and crucified; how Chaereas and his bosom friend Polycharmus went on a warship to Miletus in search of Callirhoe but were captured and sold as slaves to Mithridates, satrap of Caria.

Now Mithridates too had fallen in love with Callirhoe on seeing her at Miletus. On returning to Caria he discovers the identity of his slave Chaereas just in time to save him from crucifixion because of an uprising of his fellow-slaves, and tells him that his wife is now married to Dionysius. Chaereas writes a letter to Callirhoe full of penitence and of love and Mithridates forwards it by Hyginus, his faithful slave, adding another letter of his own promising Chaereas and Callirhoe his aid. Unfortunately these letters fall into the hands of Dionysius himself and that noble prince, in his mad passion for his wife, conceals from her the news that Chaereas is alive and makes a plot for the protection of his own interests. He appeals to Pharnaces, governor of Lydia and Ionia, who is also in love with Callirhoe, to help a scheme he has made. Pharnaces thus prompted writes a letter to Artaxerxes, King of the Persians, accusing Mithridates of trying to corrupt Dionysius’ wife. The great King then summons Mithridates to a trial for plotting adultery and sends also for Dionysius and Callirhoe.

The court scene is full of magnificence and surprises. Mithridates has no fear because in answer to the denunciations of Dionysius he is able to produce as a witness Chaereas who swears to his innocence and friendship. Mithridates is acquitted and departs. Then the King dismisses the court for five days before adjudging whose wife Callirhoe is to be since now she has two living husbands. Meanwhile he intrusts the lady for safe keeping to his wife, Statira. Dionysius is torn between the promptings of passion and reason. Chaereas is in despair at the possibility of losing Callirhoe again. And Artaxerxes, the King, like all the other great gentlemen in the story, falls madly in love with Callirhoe for her beauty.

The King’s passion makes him postpone the court trial a month on the pretext of a dream which demanded sacrifice to the gods. His eunuch tries to persuade the heroine to do herself the honor of submitting to the King’s embraces, but only horrifies and offends her purity. Now Fortune again takes a hand in separating once more Chaereas and Callirhoe, for a revolt of the Egyptians is announced, the King must be off to war, and as usual the queen and her suite go with him. Callirhoe accompanies the queen by royal orders.

Dionysius of course serves as one of the King’s generals. He has a crafty piece of news conveyed to Chaereas that in reward for his faithful service the King had given him Callirhoe. Chaereas, believing this false story, and no longer caring to live, enlists with the faithful Polycharmus in the Egyptian army to fight against his rival. He is allowed to collect an army of three hundred Greeks in memory of Thermopylae and with them captures Tyre. News of this loss makes the Persian King so anxious that he decides not to travel with all his retinue, but to leave the women on the little island of Aradus. Chaereas who is proving a valiant warrior soon takes the island and discovers Callirhoe among his captives. Both faint on seeing each other but since joy never kills, they soon recover and reunited tell all and forgive all.