A private, 31, was in the retreat from Mons, was blown up by a shell and buried in May, 1915, went back to the front after two months leave, was knocked unconscious by a shell December, 1916. He came to himself two days later in the hospital, but remained confused and lethargic. In England, December 21, his legs were still weak and walking was unsteady. The right pupil reacted neither to light nor to accommodation and was irregular, eccentric, and dilated. The left pupil showed the Argyll-Robertson reaction. There was early primary optic atrophy. The right knee-jerk was slightly exaggerated. The vibration sense was reduced over sacrum and malleoli. At this time the man’s mental condition was practically normal.
The Wassermann reaction of the serum and spinal fluid proved positive. Improvement followed rest, iodide, mercury, and seven injections of salvarsan. By the middle of February he was able to walk well. The right pupil regained its power to react to accommodation, but remained inactive to light. Meanwhile, the left pupil had regained a slight power to react to light.
Re treatment of syphilis, both Thibierge and Lépine give warning of some bad results with arsenobenzol treatment, though Thibierge states that the number of serious accidents and especially of deaths has diminished more and more now that no arsenobenzol (drug No. 914) is given. Encephalitis is the gravest of the untoward results of injection, sometimes appearing in young and vigorous subjects. Hemorrhagic encephalitis appears to occur more frequently after the second injection than after the first, and according to Thibierge may be especially suspected in subjects who after the first injection present much fever, congestion of face, and cutaneous eruptions. Treatment in these cases should be suspended or given in moderate doses.
Shell-explosion: Neurosyphilis. Fit for light duty.
Case 25. (Hurst, April, 1917.)
A corporal, 26, blown up by a shell December 7, 1916, was admitted to the hospital on the 13th, dazed and with symptoms of a left-sided hemiplegia of organic origin. The right pupil was larger than the left. There was a bruise of the scalp in the right parietal region. The man had had syphilis at 16. The Wassermann reaction of the serum was strongly positive. Rest, salvarsan, mercury, and iodides were given, and the general symptoms and hemiplegia gradually disappeared, until on December 12 there was only a moderate weakness of the left side, with knee-jerks in excess, abdominal reflexes absent, and the Babinski reaction.
The Wassermann reaction was still strongly positive. Salvarsan, mercury, and iodide were continued. January 6, 1917, the plantar reflex had become flexor. The abdominal reflex returned. Babinski’s second sign (combined flexion of thigh and pelvis) was now the only evidence of organic disease. Further antisyphilitic treatment removed this sign also. February 28, the man was discharged fit for light duty, with unequal pupils and positive Wassermann reaction, and a complete amnesia for the four weeks following his blowing up in the trenches.
Re fitness for light duty, see remarks on [Case 20] concerning desk duty for certain tabetics.
Re the premature or unexpectedly early appearance of neurosyphilis under war conditions, the early claims of some authors have not been maintained. In the above instance, the infection was at 16 and the shell explosion occurred at 26, namely, at about the right interval for the development of neurosyphilitic signs. Gerver states that military service brings out the lesions of paresis earlier than they would otherwise come. Bonhoeffer has been unable to show that cerebrospinal syphilis is favored in its development by the exhaustion factor.