Zoonomia; Or, the Laws of Organic Life, Vol. I

by Erasmus Darwin

The juices of some bitter vegetables, as of the poppy and the laurocerasus, and the ardent spirit produced in the fermentation of the sugar found in vegetable juices, are so agreeable to the nerves of the stomach, that, taken in a small quantity, they instantly pacify the sense of hunger; and the inattention to external stimuli with the reveries of imagination, and sleep, succeeds, in the same manner as when the stomach is filled with other less intoxicating food.

This inattention to the irritative motions occasioned by external stimuli is a very important circumstance in the approach of sleep, and is produced in young children by rocking their cradles: during which all visible objects become indistinct to them. An uniform soft repeated sound, as the murmurs of a gentle current, or of bees, are said to produce the same effect, by presenting indistinct ideas of inconsequential sounds, and by thus stealing our attention from other objects, whilst by their continued reiterations they become familiar themselves, and we cease gradually to attend to any thing, and sleep ensues.

[2]. After great fatigue or inanition, when the stomach is suddenly filled with flesh and vegetable food, the inattention to external stimuli, and the reveries of imagination, become so conspicuous as to amount to a degree of intoxication. The same is at any time produced by superadding a little wine or opium to our common meals; or by taking these separately in considerable quantity; and this more efficaciously after fatigue or inanition; because a less quantity of any stimulating material will excite an organ into energetic action, after it has lately been torpid from defect of stimulus; as objects appear more luminous, after we have been in the dark; and because the suspension of volition, which is the immediate cause of sleep, is sooner induced, after a continued voluntary exertion has in part exhausted the sensorial power of volition; in the same manner as we cannot contract a single muscle long together without intervals of inaction.

[3]. In the beginning of intoxication we are inclined to sleep, as mentioned above, but by the excitement of external circumstances, as of noise, light, business, or by the exertion of volition, we prevent the approaches of it, and continue to take into our stomach greater quantities of the inebriating materials. By these means the irritative movements of the stomach are excited into greater action than is natural; and in consequence all the irritative tribes and trains of motion, which are catenated with them, become susceptible of stronger action from their accustomed stimuli; because these motions are excited both by their usual irritation, and by their association with the increased actions of the stomach and lacteals. Hence the skin glows, and the heat of the body is increased, by the more energetic action of the whole glandular system; and pleasure is introduced in consequence of these increased motions from internal stimulus. According to Law 5. Sect. [IV]. on Animal Causation.

From this great increase of irritative motions from internal stimulus, and the increased sensation introduced into the system in consequence; and secondly, from the increased sensitive motions in consequence of this additional quantity of sensation, so much sensorial power is expended, that the voluntary power becomes feebly exerted, and the irritation from the stimulus of external objects is less forcible; the external parts of the eye are not therefore voluntarily adapted to the distances of objects, whence the apparent motions of those objects either are seen double, or become too indistinct for the purpose of balancing the body, and vertigo is induced.

Hence we become acquainted with that very curious circumstance, why the drunken vertigo is attended with an increase of pleasure; for the irritative ideas and motions occasioned by internal stimulus, that were not attended to in our sober hours, are now just so much increased as to be succeeded by pleasurable sensation, in the same manner as the more violent motions of our organs are succeeded by painful sensation. And hence a greater quantity of pleasurable sensation is introduced into the constitution; which is attended in some people with an increase of benevolence and good humour.

If the apparent motions of objects is much increased, as when we revolve on one foot, or are swung on a rope, the ideas of these apparent motions are also attended to, and are succeeded with pleasureable sensation, till they become familiar to us by frequent use. Hence children are at first delighted with these kinds of exercise, and with riding, and failing, and hence rocking young children inclines them to sleep. For though in the vertigo from intoxication the irritative ideas of the apparent motions of objects are indistinct from their decrease of energy: yet in the vertigo occasioned by rocking or swinging the irritative ideas of the apparent motions of objects are increased in energy, and hence they induce pleasure into the system, but are equally indistinct, and in consequence equally unfit to balance ourselves by. This addition of pleasure precludes desire or aversion, and in consequence the voluntary power is feebly exerted, and on this account rocking young children inclines them to sleep.

In what manner opium and wine act in relieving pain is another article, that well deserves our attention. There are many pains that originate from defect as well as from excess of stimulus; of these are those of the six appetites of hunger, thirst, lust, the want of heat, of distention, and of fresh air. Thus if our cutaneous capillaries cease to act from the diminished stimulus of heat, when we are exposed to cold weather, or our stomach is uneasy for want of food; these are both pains from defect of stimulus, and in consequence opium, which stimulates all the moving system into increased action, must relieve them. But this is not the case in those pains, which arise from excess of stimulus, as in violent inflammations: in these the exhibition of opium is frequently injurious by increasing the action of the system already too great, as in inflammation of the bowels mortification is often produced by the stimulus of opium. Where, however, no such bad consequences follow; the stimulus of opium, by increasing all the motions of the system, expends so much of the sensorial power, that the actions of the whole system soon become feebler, and in consequence those which produced the pain and inflammation.

[4]. When intoxication proceeds a little further, the quantity of pleasurable sensation is so far increased, that all desire ceases, for there is no pain in the system to excite it. Hence the voluntary exertions are diminished, staggering and stammering succeed; and the trains of ideas become more and more inconsistent from this defect of voluntary exertion, as explained in the sections on sleep and reverie, whilst those passions which are unmixed with volition are more vividly felt, and shewn with less reserve; hence pining love, or superstitious fear, and the maudling tear dropped on the remembrance of the most trifling distress.

[5]. At length all these circumstances are increased; the quantity of pleasure introduced into the system by the increased irritative muscular motions of the whole sanguiferous, and glandular, and absorbent systems, becomes so great, that the organs of sense are more forcibly excited into action by this internal pleasurable sensation, than by the irritation from the stimulus of external objects. Hence the drunkard ceases to attend to external stimuli, and as volition is now also suspended, the trains of his ideas become totally inconsistent as in dreams, or delirium: and at length a stupor succeeds from the great exhaustion of sensorial power, which probably does not even admit of dreams, and in which, as in apoplexy, no motions continue but those from internal stimuli, from sensation, and from association.