In November of the same year, he made a third expedition in the vicinity of Lake Eyre, but there is little of interest attaching to the Journal of this trip, as his course was mostly over closely explored country. He reached the Neale again, and instituted a survey of the promising pastoral country he had traversed during his last trip, approaching at times to within sight of what he calls in his Journal Lake Torrens, but which in reality was what is now known as Lake Eyre. All these minor expeditions of Stuart's may be looked upon as preparatory to his great struggle to find an available passage through the unknown fastnesses of the centre of the continent.

It was in 1860 that Stuart made the first of his daring and stubborn attempts to cross Australia from south to north. The South Australian Government had offered a standing reward of 2,000 pounds for the man who should first succeed in this undertaking.

Stuart's party on his first trip was but a very small one: three men in all, with but thirteen horses. It reads lilliputian compared with the princely cavalcade that later on set out with Burke to travel over comparatively well-known country, involving only a short excursion through a land without natural difficulties or obstacles; and yet it actually achieved the greatest part of the task set it.

Stuart started from Chambers Creek, but for part of the journey he was of course travelling over country that was fairly well-known by that time. After passing the Neale, he entered untrodden country, which proved to be good available pastoral land. Numerous well-watered creeks were passed, which were named respectively the Frew, the Finke, and the Stevenson, and on the 6th of April they reached a hill of a remarkable shape, which had for some time attracted and excited their attention and curiosity. They found it to be a column of sandstone, on the apex of a hill. The hill was but a low one of a few hundred feet in height, but the sandstone column that surmounted it was one hundred and fifty feet in height and twenty feet in width. This striking object was named by Stuart Chambers Pillar, to commemorate a friend who had assisted him greatly in his explorations. It stood amongst other elevations of fantastic shapes and grotesque formations, resembling ruined forts and castles. On the 9th of April they sighted two remarkable bluffs, and on the 12th reached the range of which the bluffs formed the centre. The eastern bluff was called Brinkley Bluff and the western Hanson Bluff; the range, which is now well-known as a leading geographical feature of Australia, and on which the most elevated peaks in the interior have since been found, Stuart named the MacDonnell Range, after the then Governor of South Australia. The little band crossed the range, which was rough but had good grass on its slopes. There was, however, a scarcity of water; for they were now approaching the tropical line, and on reaching the northern slope of the range found themselves amongst spinifex and scrub, and obliged to undergo two nights without water for the horses. At a high peak, which was named Mount Freeling, they found a small supply; and as it was now evident that there was dry country ahead, a more careful search was made before pushing any further forward, in order to ensure certain means of retreat. Fortunately they found, amongst some ledges of rock, a large natural reservoir, which promised to be permanent, and capable of supplying their wants on their homeward way.

On the 22nd of April, Stuart camped in the centre of Australia, on the spot which his former leader, Sturt, had vainly undergone so much suffering to reach; and his feeling of elation must have been tempered with regret that his old leader was not then with him to share this success. About two miles and a half to the North-North-East there was a tolerably high hill which he called in reality Central Mount Sturt. It is now, however, erroneously called Stuart, owing to the publishers of his diary having misread his manuscript.

Having, in company with his tried companion Kekwick, climbed the mount, he erected a cairn of stones at the top and hoisted the Union Jack. They then recommenced their northern journey. That night they camped without finding water, but the next morning were lucky enough to get a permanent supply. Then ensued much delay, caused by fruitless attempts to strike either to the eastward or the westward. Stuart tried on several occasions to reach the head of the Victoria River, but failed, and sacrificed some horses. On a creek he called the Phillips, some natives were encountered who, according to Stuart, made and answered a masonic sign.

To the north of this spot, the explorers came to a large gum-tree creek, with very fair-sized sheets of water in it. As they followed down, they passed an encampment of natives, but kept steadily on their course without interfering with them. Not finding any water lower down the creek, the party had to return, and when close to the creek at the point where they had crossed that morning, they were suddenly surrounded by a mob of armed and painted savages, who had emerged unexpectedly from concealment in a clump of scrub. To all attempts at peaceful parley they returned showers of boomerangs and clubs, until the whites were compelled in self-defence to fire on them. Even then they were not deterred from following the party, even up to the camp of the night before. This incident caused Stuart to hesitate. His party was so small that the loss or even disablement of one man would have crippled the expedition; and they had already lost a good many horses. He therefore wisely decided to fall back, as they had penetrated far enough to prove that the passage of the continent could be effected with a few more men. It was on the 27th of June that he began his homeward march, and on the 26th of August he reached Brodie's camp at Hamilton Springs, with the strength of all much reduced, and Stuart himself suffering from scurvy.

After the result of Stuart's journey had been reported in Adelaide, and it was seen how inadequate means only had led to his defeat, the Government voted 2,500 pounds to equip a better-organized party; of this he was to take command.

Stuart judged it best to keep his old track by way of the Finke and the Hugh. On the 12th of April they arrived at the Bonney, and finding it running strong, with abundance of good feed on the banks, they were betrayed into following it down; but it soon spread abroad and was lost in a large plain. Leaving the Bonney, they adhered to the old route, and reached Tennant's Creek on the 21st of April, and four days afterwards they were on the scene of the attack that had been made on them at Attack Creek. But although the tracks of the natives were numerous, the explorers were, at this time, permitted to pass on in peace. Keeping at the foot of the low range, which there has an approximate northerly and southerly direction, Stuart crossed many creeks which promised long courses where they formed in the range, but which were all alike lost when they reached the level country. On the 4th of May they attained to the northern termination of this range, which he called the Ashburton Range. Here he made several attempts to the north and north-west, but could discover neither water nor watercourses in those directions; nothing indeed but plains, beautifully grassed, but heavy to ride over and yielding under the horses' feet. Beyond these plains, the country changed for the worse, and became sandy and scrubby. On the 16th of May he encountered a new description of scrub that grew in a very obstructive manner, and is now known as Stuart's Desert Hedgewood.

On the 23rd he found a magnificent sheet of permanent water which he called the Newcastle Waters, and at first he judged that a clear way north was now assured. But he was deluded, for beyond these waters he could not advance his party a mile; north, north-east, and north-west, there was the one outlook -- endless grassy plains, terminating in dense scrubby forest country. He had to give up all hope for the present, and return to Adelaide.