[LESSON VI]

CHEMISTRY OF METABOLISM


Meaning of metabolism

Metabolism is a word used to describe all processes that take place within the body from the time food is absorbed from the digestive organs until it is passed out of the body through some of the excretory channels. To be more accurate, it means the sum of both the anabolic, or constructive, and the catabolic, or destructive, processes that continually go on in the animal body.

Distinction between anabolism and catabolism

The process of metabolism is chiefly one of tearing apart, or of breaking down, complex chemical substances into simpler forms of matter. Formerly, all processes in animal life were considered to be those of tearing down, or of simplifying, chemical compounds; while plant life was considered to be chiefly the process of building up complex substances from simpler forms of matter. This distinction, however, is rather general with many exceptions. The two terms, "anabolism" and "catabolism" are sometimes used to distinguish between the processes of building up complex chemical compounds, and the oxidizing or tearing down of such compounds by effort or activity. Thus, the formation of muscular tissue from the digested proteid materials would be a process of anabolism, or construction, while the conversion of glucose in the muscle-cells, into carbon dioxid and water would be an example of catabolism, or destruction.

Catabolism a process of oxidation

The process of catabolism is, in general, one of oxidation; that is, oxygen is added to the chemical compounds taken from the food we eat, forming simpler substances which are excreted from the body as waste-products. Oxidized carbon in the body forms carbon dioxid; hydrogen is oxidized into the form of water, while nitrogen leaves the body in the more complex and incompletely oxidized substance known as urea, the chemical formula of which is COH4N2. A small portion of nitrogen leaves the body in the form of uric acid, C5H4N4O3.