In the meantime her husband Alfonso had decided, unfortunately for himself, to obey Alexander's command and return to his wife—perhaps because he really loved her. The Pope ordered him to go to Spoleto by way of Foligno, and then to come with his spouse to Nepi, where he himself intended to be. The purpose of this meeting was to establish his daughter as sovereign there also.

Nepi had never been a baronial fief, although the prefects of Vico and the Orsini had held the place at different times. The Church through its deputies governed the town and surrounding country. When Alexander was a cardinal his uncle Calixtus had made him governor of the city, and such he remained until he was raised to the papal throne, when he conferred Nepi upon Cardinal Ascanio Sforza. The neatly written parchment containing the municipal statute confirming Ascanio's appointment, which is dated January 1, 1495, is still preserved in the archives of the city. At the beginning of the year 1499, however, Alexander again assumed control of Nepi by compelling the castellan, who commanded the fortress for the truant Ascanio, to surrender it to him. He now invested his daughter with the castle, the city, and the domain of Nepi.[66] September 4, 1499, Francesco Borgia, the Pope's treasurer, who was also Bishop of Teano, took possession of the city in her name.

September 25th Alexander himself, accompanied by four cardinals, went to Nepi. In the castle, which he had restored, he met Lucretia and her husband, and also her brother Don Giuffrè. He returned to Rome almost immediately—October 1st. On the tenth he addressed a brief from there to the city of Nepi, in which he commanded the municipality thenceforth to obey Lucretia, Duchess of Biselli, as their true sovereign. On the twelfth he sent his daughter a communication in which he empowered her to remit certain taxes to which the citizens of Nepi had hitherto been subject.[67]

Lucretia, therefore, had become the mistress of two large domains—a fact which clearly shows that she stood in high favor with her father. She did not again return to Spoleto, but entrusted its government to a lieutenant. Although Alexander made Cardinal Gurk legate for Perugia and Todi early in October, he reserved Spoleto for his daughter. Later, August 10, 1500, he made Ludovico Borgia—who was Archbishop of Valencia—governor of this city, without, however, impairing his daughter's rights to the large revenue which the territory yielded.

As early as October 14th Lucretia returned to Rome. November 1, 1499, she gave birth to a son, who was named, in honor of the Pope, Rodrigo. Her firstborn was baptized with great pomp November 11th in the Sistine Chapel—not the chapel now known by that name, but the one which Sixtus IV had built in S. Peter's. Giovanni Cervillon held the child in his arms, and near by were the Governor of Rome and a representative of the Emperor Maximilian. All the cardinals, the ambassadors of England, Venice, Naples, Savoy, Siena, and the Republic of Florence were present at the ceremony. The governor of the city held the child over the font. The godfathers were Podocatharo, Bishop of Caputaqua, and Ferrari, Bishop of Modena.

In the meantime, October 6th, Louis XII had taken possession of Milan, Ludovico Sforza having fled, on the approach of the French forces, to the Emperor Maximilian. In accordance with his agreement with Alexander, the king now lent troops to Cæsar Borgia to enable him to seize the Romagna, where it was proclaimed that the vassals of the Church, the Malatesta of Rimini, the Sforza of Pesaro, the Riario of Imola and Forli, the Varano of Camerino, and the Manfredi of Faenza had forfeited their fiefs to the Pope.

Cæsar went to Rome, November 18, 1499. He stayed in the Vatican three days and then set forth again to join his army, which was besieging Imola. It was his intention first to take this city and then attack Forli, in the castle of which the mistress of the two cities, Catarina Sforza, had established herself for the purpose of resisting him.

While he was engaged in his campaigns in Romagna, his father was endeavoring to seize the hereditary possessions of the Roman barons. He first attacked the Gaetani. From the end of the thirteenth century this ancient family had held large landed estates in the Campagna and Maritima. It had divided into several branches, one of which was settled in the vicinity of Naples. There the Gaetani were Dukes of Traetto, Counts of Fundi and Caserta, and likewise vassals and favorites of the crown of Naples.

Sermoneta, the center of the domain of the Gaetani family in the Roman Campagna, was an ancient city with a feudal castle, situated in the foothills of the Volscian mountains. Above it and to one side were the ruins of the great castle of Norba; below were the beautiful remains of Nymsa; while at its foot, extending to the sea, lay the Pontine marshes. The greater part of this territory, which was traversed by the Appian Way, including the Cape of Circello, was the property of the Gaetani, to whom it still belongs.

At the time of which we are speaking it was ruled by the sons of Honoratus II, a powerful personality, who had raised his house from ruin. He died in the year 1490, leaving a widow, Catarina Orsini, and three sons—Nicola the prothonotary; Giacomo, and Guglielmo. His daughter Giovanella was the wife of Pierluigi Farnese and mother of Giulia. Nicola, who had married Eleonora Orsini, died in the year 1494; consequently, next to the prothonotary Giacomo, Guglielmo Gaetani was head of the house of Sermoneta.