Emeticks and Catharticks were equally here useless, and often hurtful, in exhausting the Patient’s Strength, by their fatal over-working.

The Cordials and Sudorificks were the only Remedies to which we had recourse, which nevertheless could be of no Service, or at the most prolong the last Moments but for a few Hours.

Second Class.

The second Class of the Diseased that we attended during the Course of this fatal Sickness, contains such as at first had the Shiverings, as the preceding, and the same sort of Stupidity, and heavy Pain in the Head; but the Shiverings were followed by a Pulse quick, open, and bold, which nevertheless was lost upon pressing the Artery ever so little. These Sick felt inwardly a burning Heat, whilst the Heat without was moderate and temperate; the Thirst was great and inextinguishable; the Tongue white, or of an obscure red; the Voice hasty, stammering, impetuous; the Eyes reddish, fixed, sparkling; the Colour of the Face was of a red sufficiently fresh, and sometimes inclining to livid; the Sickness at the Stomach was frequent, tho’ much less than in those of the preceding Class; the Respiration was frequent, laborious, or great and rare, without Coughing or Pain; Loathings; Vomitings, bilious, greenish, blackish, bloody; the Courses of the Belly of the same Sort, but without any Tension or Pain; Ravings, or phrenetick Deliria; the Urine frequently natural, sometimes troubled, blackish, whitish, or bloody; the Sweat, which seldom smelt badly, and which was far from giving Ease to the Sick, that it always weakned them; in certain Cases Hemorrhages, which, however moderate, have been always fatal; a great Decay in the Strength, and above all, an Apprehension so strong of dying, that these poor Creatures, were incapable of any Comfort, and looked on themselves, from the first Moment of their being attacked, as destined to certain Death. But that which deserves to be well observed, and which has always seemed to characterise and distinguish this Disease from all others, is, that almost all had at the Beginning, or in the Progress of this Distemper, very painful Buboes, situated commonly below the Groin, sometimes in the Groin or Arm-pits, or in the Parotide, Maxillar, or jugular Glands; as likewise Carbuncles, especially on the Arms, Legs or Thighs, small, white, livid, black Pustles, dispersed over all the Surface of the Body.

It was very rare to see any of the diseased of this Second Class escape, though they supported themselves a little longer than those of the preceding; they perished almost all with the Marks of a gangren’d Inflammation, especially in the Brain and Thorax; and that which was most singular is, that the stronger, fatter, fuller, and more vigorous they were, the less we had to hope.

As to the Remedies, they bore Bleeding no better than those of the First Class; at least if they were not blooded at the very first Instant of their being taken Sick: It was evidently hurtful to ’em; they grew pale, and fell even in the time of their first Bleeding, or a little while after, into such Faintings, as could not in most of them be imputed to any Fear, Repugnance, or Distrust, since they demanded with Earnestness to have a Vein opened.

All Emeticks, if we except Ipecacuanha, were very often more hurtful than useful; causing such fatal Irritations and Excesses in operating, as we could neither moderate or stop.

The Catharticks that were a little strong and active, were attended with the same Inconveniences.

Such as we prescribed in the Form of a laxative Ptisan, as well as plentiful Draughts, that were diluting, nitrous, cooling, and gently alexiterial, gave some Relief, but did not hinder the Return of the Symptoms.

All Cordials and Sudorificks, if they were not soft, gentle and benign, did nothing but promote the Progress of the inward Inflammations.