La Cosa was created alguazil mayor of the territory he and Vespucci had coasted, and finding Ojeda in want—both of money and an opportunity to display his prowess as a fighter—he generously shared his fortune with him and fitted out a fleet containing a ship and two small brigantines. Thenceforth, as fate willed it, the great-hearted pilot and the fiery cavalier were inseparable until cut down by death. In the month of November, 1509, they set sail from Santo Domingo with their three vessels and three hundred men. La Cosa piloted the little fleet into a safe harbor, as he knew the coast well from two previous visits to Terra Firma, but he endeavored to induce Ojeda to attempt a settlement farther on towards the Isthmus of Darien, as the Indians of this region were very ferocious and used poisoned arrows.

Ojeda, however, would not be turned from his purpose, which was to acquire a large number of slaves, either by stratagem or force. After the monks who accompanied his command had read a requisition to the savages, requiring them to submit gracefully and be converted, if they did not wish to incur the vengeance of the King of Spain, the Pope of Rome, and their emissaries there assembled, finding them obdurate, Ojeda gave the command to attack. The Indians, by this time, had assembled in great force, and if they understood the message (which was not likely, as it was in Spanish, a language they had never heard before) they manifested no inclination to heed its warnings. They brandished their spears, shot their arrows, and yelled defiance to the invaders. This was more than the rash Ojeda could endure, and he dashed headlong at the naked enemy without waiting for his men to follow.

Only the gallant La Cosa was with him at first, continually remonstrating with his friend for his temerity, but fighting bravely at his side. The old pilot was a man of peace, but he was destined to die a violent and a horrible death. While pressing forward in advance of their men, the retreat of Ojeda and La Cosa was cut off by the wily savages, who had pretended to retire to the hills, whence they soon returned in great force. La Cosa took refuge in a hut, where he gallantly defended himself until a poisoned arrow pierced his breast and he fell to the ground. One companion survived, to whom he said, as he felt the chill of death creeping over him, "Brother, since God hath protected thee from harm, sally out and fly; and if ever thou shouldst see Alonzo de Ojeda, tell him of my fate."

Thus expired Juan de la Cosa, former companion of Columbus and Vespucci, able pilot, skilled cartographer, loyal till death to the man who had led him into the forest where he met that fatal arrow.

It is claimed by some that Vespucci and La Cosa made two voyages together, in the years 1505 and 1507, but this is doubtful. After their return from the voyage of 1499-1500 they separated, Amerigo to take service with the King of Portugal, and La Cosa, upon the completion of his chart and after his return from the Bastidas expedition of 1500-1501, settling down to the enjoyment of his fortune. The third famous member of the trio, Alonzo de Ojeda, obtained authority from the king to colonize Coquibacoa, on the coast of Terra Firma, and received in addition a grant of land six leagues square in the island of Hispaniola.

The former venture had not been considered a success, but the merchants of Seville and Cadiz were persuaded to once more try their fortunes with the brave cavalier Ojeda, and fitted out for him a fleet of four large vessels. In command of these he set sail, in the year 1502, and after touching at Cumana, where he pillaged the Indians and took many prisoners, he proceeded to Coquibacoa. Finding the place unsuited for a settlement, he went farther westward and attempted a colony at Bahia Honda, building there a fortress and huts for his people. The Indians were hostile at first, but gold was found in abundance—so much of it, in fact, that the adventurers began to quarrel over it, and soon came to blows. Ojeda, as usual, was foremost in the fight that followed, and, as his company turned against him, he was entrapped on one of the caravels and placed in irons. Then the entire company sailed for Hispaniola, intending to submit the cause of their dissension, which was their strong-box full of gold, to the courts of that island for a decision. They arrived at a port on the western coast of Hispaniola, and in the night the manacled Ojeda slipped overboard into the water, intending to swim ashore and make his escape. The fetters on his feet were heavy, however, though his arms were free, and he was nearly drowned before his companions, hearing his cries for help, pulled him out of the water and again confined him in the hold of the vessel.

Taken to the city of Santo Domingo, he was placed on trial for attempting to defraud the government, and the decision was against him. He was not only deprived of his lands, but was stripped of everything he owned. For several years thereafter he roamed about the island, and made occasional voyages, but as a penniless, rather than an influential, adventurer. His good friend, the "ungodly bishop," Fonseca, was still in power, but inaccessible through the great distance that separated them. One happy day, however, Ojeda met La Cosa, who was then in the enjoyment of a considerable fortune, and who, with the reckless generosity for which sailors are proverbial, placed all his means at his disposal. He went to Spain, where he saw the bishop, secured a fleet (as already mentioned), and in it sailed for Santo Domingo, where he was met by his partner, and together the soldier and the sailor set out for Terra Firma.

Before they left the island, however, Ojeda must needs plunge himself into another difficulty by picking a quarrel with a rival discoverer, Nicuesa, whom he challenged to fight a duel. It seems that King Ferdinand had granted territory in Terra Firma to both these men; and, though there was certainly room enough and to spare in that vast region, they began to dispute over their perspective boundaries before they had staked them out. The hot-headed Ojeda was a skilled swordsman, but Nicuesa was artful enough to avoid an encounter, in which there was little doubt he would be killed, by insisting that each contestant should deposit five thousand castellanos with an umpire before engaging in the fight. As this was a larger sum than poor Ojeda could raise—which, of course, Nicuesa knew full well—the irate cavalier was obliged to sail without having obtained satisfaction.

This was the expedition that ended so disastrously, as narrated in a previous chapter. The Spaniard who was charged with La Cosa's last message to Ojeda was the only survivor of seventy who had followed the rash commander in his headlong attack. What had become of Ojeda himself none of the survivors could tell, for several days passed without news of him. His body was not to be found among the slain, and no one who knew him believed that the Indians could have captured him alive. He had fought like a tiger to reach and defend his friend La Cosa, but had been borne back by the thronging savages, and since then nothing had been heard of him. The woods and shore were searched by scouts, and he was finally found extended on some mangrove roots on the borders of the forest. He was in such an exhausted state that he could not speak, but, intrepid to the last, still clung to his buckler, and in his right hand grasped the good sword with which he had cut his way through the savage hordes.

Although famished, and so weak that he could not stand, it was discovered that he had not received a single wound; but on his shield were seen the dents made by more than three hundred arrows. His rescue had scarcely been effected before the ships of his deadly rival, Nicuesa, sailed into the harbor; but, instead of taking advantage of Ojeda's defenceless condition, the high-minded hidalgo offered to join with him in an attack upon the savages, in order to avenge his defeat. Combining their forces, the two erstwhile enemies fell upon the Indians while they were asleep, slaughtered an immense number, and then, after plundering their dwellings set them on fire.