“The glandular elements in this area and the hair follicles appear normal.
“Toward the deeper layers and the subcutaneous connective tissues appear isolated areas of round-cell infiltration separated by masses of fibrous connective tissue, much of which is of new formation, as indicated by the nucleated character of the elongated cells. There are areas of diffuse round-cell infiltration.
“In this portion of the corium there is also to be found a large number of vacuolated areas varying very greatly in size, and which are surrounded by membranous fibrous-tissue elements, much of which is likewise of new formation, as indicated by the character of its cells.
“These vacuoles doubtless represent the areas containing the masses of paraffin which have been split up by the new formation of fibrous tissue. Between the vacuolated areas can be seen actual infiltration by true fat cells.
“In many spots the fibrous-tissue formation has proceeded to the point of thick bands containing but few nucleated cells. [Fig. 288a], which is a photomicrograph of this portion of the section, shows these changes.
“In one of the foci of round-cell infiltration which have been surrounded and invaded by bands of new fibrous tissue there are numerous giant cells of the so-called ‘foreign-body’ type. This is shown in [Fig. 288b].
Fig. 288a.—Microphotograph showing Fibromatosis. × 40.
