Vée asserts that if to a solution of eserine, a little potash, lime, or carbonate of sodium be added, there is developed a red colour which rapidly increases in intensity. This colour is transient, passing into yellow, green and blue. If chloroform is shaken with such coloured solution, it takes up the colour; ether on the other hand remains uncoloured.
Uses—Calabar has been hitherto chiefly employed as an ophthalmic medicine, for the purpose of contracting the pupil. It has however been occasionally administered in tetanus and in neuralgic, rheumatic, and other diseases.
Adulteration—Other seeds are sometimes fraudulently mixed with Calabar beans. We have noticed in particular those of a Mucuna and of the Oil Palm, Elæis guineensis Jacq. The slightest examination suffices for their detection.
KINO.
Kino, Gum Kino, East Indian Kino; F. and G. Kino.
Botanical Origin—Pterocarpus Marsupium Roxb., a handsome tree 40 to 80 feet high, frequent in the central and southern parts of the Indian Peninsula and also in Ceylon, and affording a valuable timber. In the Government forests of the Madras Presidency, it is one of the reserved trees, the felling of which is placed under restrictions.
Pt. indicus Willd., a tree of Southern India, the Malayan Peninsula and the Indian and Philippine Islands, is capable of yielding kino, and is the source of the small supplies of that drug that were formerly shipped from Moulmein.
Several other plants afford substances bearing the name of Kino, which will be noticed at the conclusion of the present article.
History—The introduction of kino into European medicine is due to Fothergill, an eminent physician and patron of economic botany of the last century. The drug which Fothergill examined was brought from the river Gambia in West Africa as a rare sort of Dragon’s Blood, and was described by him in 1757[766] under the name of Gummi rubrum astringens Gambiense. It had been noticed at least twenty years before as a production of the Gambia, by Moore, factor to the Royal African Company, who says that the tree yielding it is called in the Mandingo language Kano.[767] Specimens of this tree were sent to England in 1805 by the celebrated traveller Mungo Park, and recognized some years later as identical with the Pterocarpus erinaceus of Poiret.
It seems probable that African kino continued to reach England for some years, for we find “Gummi rubrum astringens” regularly valued in the stock of a London druggist[768] from 1776 to 1792.