In the roots of the Compositæ inulin is accompanied, according to Popp,[1415] by two closely allied substances, Synanthrose, C₁₂H₂₂O₁₁ + H₂O, and Inuloïd, C₆H₁₀O₅ + H₂O. Synanthrose is soluble in dilute alcohol, devoid of any rotatory power, and deliquescent. Inuloïd is much more readily soluble in water than inulin. Both these substances are probably present in elecampane.

Inulin is widely distributed in the perennial roots of compositæ, and has also been met with in the natural orders Campanulaceæ, Goodenovieæ (or Goodeniaceæ), Lobeliaceæ, Stylidieæ, and lastly by Kraus (1879) in the root of Ionidium Ipecacuanha St. Hilaire, Violaceæ; the formerly so-called Ipecacuanha alba lignosa ([see p. 375, note 4]).

Uses—Elecampane is an aromatic tonic, but as a medicine is now obsolete. It is chiefly sold for veterinary practice. In France and Switzerland (Neuchâtel), it is employed in the distillation of Absinthe.

Substitutes—Dioscorides in speaking of Costus root states that it is often mixed with that of elecampane of Kommagene (north-western Syria). The former, derived from Aplotaxis[1416] auriculata DC. (A. Lappa Decaisne, Aucklandia Costus Falconer), is remarkably similar to elecampane both in external appearance and structure. Costus is an important spice, incense and medicine in the east from the antiquity down to the present day;[1417] it would be of great interest to examine it chemically with regard to elecampane.

RADIX PYRETHRI.

Pellitory Root, Pellitory of Spain; F. Pyrèthre-salivaire; G. Bertramwurzel.

Botanical OriginAnacylus Pyrethrum DC. (Anthemis Pyrethrum L.), a low perennial plant with small, much divided leaves, and a radiate flower resembling a large daisy. It is a native of northern Africa, especially Algeria, growing on the high plateaux that intervene between the fertile coast regions and the desert.

History—The πύρεθρον of Dioscorides was an umbelliferous plant, the determination of which must be left to conjecture. The pellitory of modern times was familiar to the Arabian writers on medicine, one of whom, Ibn Baytar, describes it very correctly from specimens gathered by himself near the city of Constantine in Algeria. The plant, says he, called by the Berbers sandasab, is found nowhere but in Western Africa, from which region it is carried to other countries.[1418]

Pellitory root is a favourite remedy in the East, and has long been an article of export by way of Egypt to India. An Arabic name for it is Aāqarqarhā or Akulkara[1419], a word which, under slight variations, is found in the principal languages of India. In Germany, pellitory was known as early as the 12th century; it is named in the oldest printed works on materia medica. In the 13th century “pellitory of Spain” (Pelydr ysbain) was a proved “remedy for the toothache” with the Welsh physicians.[1420]

Description—The root as found in the shops is simple, 3 to 4 inches long by ⅜ to ⁴/₈ of an inch thick, cylindrical, or tapering, sometimes terminated at top by the bristly remains of leaves, and having only a few hair-like rootlets. It has a brown, rough, shrivelled surface, is compact and brittle, the fractured surface being radiate and destitute of pith. The bark, at most ¹/₂₅ of an inch thick, adheres closely to the wood, a narrow zone of cambium intervening. The woody column is traversed by large medullary rays in which, as in the bark, numerous dark resin-ducts are scattered. The root has a slight aromatic smell, and a persistent, pungent taste, exciting a singular tingling sensation, and a remarkable flow of saliva. The drug is very liable to the attacks of insects.