An analogous drug is mentioned by Paulus Ægineta[2130] in the 7th century as well as by the Arabian physicians[2131] as early as the 10th century, under the name of Kanbil or Wars. Ibn Khurdádbah, an Arab geographer, living a.d. 869-885, states that from Yemen come striped silks, ambergris, wars, and gum.[2132] It is described to be a reddish yellow powder like sand, which falls on the ground in the valleys of Yemen, and is a good remedy for tapeworm and cutaneous diseases. One writer compares it to powdered saffron; another speaks of two kinds,—an Abyssinian which is black (or violet), and an Indian which is red. Masudi,[2133] in the first half of the 10th century speaks of qinbil, which he says consists of sandy fruits of red hue. They are useful as an anthelminthic and for cutaneous diseases. A similar explanation of the qinbil is found in Qamus, a dictionary writer in the 13th century in Yemen. About the year 1216, a learned traveller, Abul Abbas Ahmad Annabati,[2134] (Annabati = the botanist) or Abul Abbas el-Nebáti, who was a native of Seville, remarks that the drug is known in the Hejaz and brought from Yemen, but that it is unknown in Andalusia and does not grow there.
Kazwini,[2135] nearly at the same period, was also acquainted with wars, a plant sown in Yemen and resembling Sesam; Constantinus Africanus likewise mentioned “huars.” Wars, Wors, Wurrus or Warras in Arabia properly signifies saffron.
In modern times, we find Niebuhr[2136] speaks of the same substance (as “wars”), stating it to be a dye-stuff, of which quantities are conveyed from Mokha to Oman.
Production—Kamala is one of the minor products of the Government forests in the Madras Presidency, but is also collected in many other parts of India. The following particulars have been communicated to us by a correspondent[2137] in the North-west Provinces:—
“ ... Enormous quantities of Rottlera tinctoria are found growing at the foot of these hills, and every season numbers of people, chiefly women and children, are engaged in collecting the powder for exportation to the plains. They gather the berries in large quantities and throw them into a great basket in which they roll them about, rubbing them with their hands so as to divest them of the powder, which falls through the basket as through a sieve, and is received below on a cloth spread for the purpose. This powder forms the Kamala of commerce, and is in great repute as an anthelminthic, but is most extensively used as a dye. The adulterations are chiefly the powdered leaves, and the fruit-stalks with a little earthy matter, but the percentage is not large. The operations of picking the fruit and rubbing off the powder commence here in the beginning of March and last about a month....”
A similar powder is collected in Southern Arabia, whence it is shipped to the Persian Gulf and Bombay. It is also brought, under the name of Wars, from Hurrur, a town in Eastern Africa, which is a great trading station between the Galla countries and Berbera.[2138] Yet the Arabian and African drug consists in most cases not of kamala, but of those dark glands which we describe further on, at [p. 575].
Description—Kamala is a fine, granular, mobile powder, consisting of transparent, crimson granules, the bright colour of which is mostly somewhat deadened by the admixture of grey stellate hairs, minute fragments of leaves and similar foreign matter. It is nearly destitute of taste and smell, but an alcoholic solution poured into water emits a melon-like odour. Kamala is scarcely acted on by water, even at a boiling heat; on the other hand, alcohol, ether, chloroform or benzol extract from it a splendid red resin. Neither sulphuric nor nitric acid acts upon it in the cold, nor does oil of turpentine become coloured by it unless warmed. It floats on water, but sinks in oil of turpentine. When sprinkled over a flame, it ignites after the manner of lycopodium. Heated alone, it emits a slight aromatic odour; if pure, it leaves after incineration about 1·37 per cent. of a grey ash.
Microscopic Structure—The granules of kamala are irregular spherical glands, 50 to 60 mkm. in diameter; they have a wavy surface, are somewhat flattened or depressed on one side, and enclose within their delicate yellowish membrane a structureless yellow mass in which are imbedded numerous, simple, club-shaped cells containing a homogeneous, transparent, red substance. These cells are grouped in a radiate manner around the centre of the flattened side, so that on the side next the observer, 10 to 30 of them may easily be counted, while the entire gland may contain 40 to 60. In a few cases, a very short stalk-cell is also seen at the centre of the base.
When the glands are exhausted by alcohol and potash, and broken by pressure between flat pieces of glass, they separate into individual cells which swell up slightly, while the membranous envelope is completely detached, and appears as a simple coherent film. After this treatment the cells, but not their membranous envelope, acquire by prolonged contact with strong sulphuric acid and iodine water a more or less brown or blue colour: the walls of the cells alone correspond therefore to cellulose. Vogl (1864) supposes that a cell of the epidermis of the fruit first develops a young cellule, which by partition is resolved into the stalk-cell and the true mother-cell of the small clavate resin-cellules. At first, the contents of the latter do not differ from the mass in which they are imbedded, and perhaps pass gradually into resin by metamorphosis of the cellular substance.
The glands of kamala are always accompanied by colourless or brownish, thick-walled, stellate hairs, two or three times as long as the glands, often containing air, which do not exhibit any peculiarity of form, but resemble the hairs of other plants, as Verbascum or Althæa.