At last, in 1859 (on the suggestion of Dr. Royle in 1839), the adventurous journeys of Clements Markham, Spruce, and Robert Cross resulted in the introduction of the Cinchona now flourishing in Madras, Bombay, and Ceylon. In 1897 British colonies produced about £43,415 worth of quinine, and the price is now only 7-1/2d. or 8d. a pound!
Such drugs as Safflower are of very ancient date. It was commonly employed in Egypt with other dyes and spices for embalming mummies. It is now used with carbonate of soda and citric acid to give a pink dye to silks and satins, and occasionally, in the form of rouge, to ladies' cheeks! How did the ancient Egyptians discover that this particular thistle-like plant (Carthamus tinctorius) had flowers from which a red dye could be extracted by a tedious process of soaking in water? The natural colour of the flowers is not red but yellow.
The history of other drugs reads like a romance. Ipecacuanha, for instance, was discovered by some unknown Indian who lived in the damp tropical forests of Brazil and New Granada. A worthy merchant in Paris obtained a little of the drug in the way of trade. Shortly afterwards he became very ill and was attended by a certain Dr. Helvetius, who was exceedingly attentive to him. The grateful merchant gave the kind-hearted physician some ipecacuanha. In the course of time the great King Louis XIV's son fell ill of dysentery, and Helvetius received 1000 louis d'or for his ipecacuanha.
A very interesting and romantic history might be written about the effect of drugs, dyes, and spices in developing trade. During the time when Britain was struggling to obtain a share of the foreign trade of Holland and France, such spices as Clove, Cinnamon, and Pepper were of the greatest importance. The Dutch, especially, adopted every possible method to keep the spice trade in their own hands. They cut down the clove, cinnamon, and other trees, in all the islands not directly under their control. They imposed the most barbarous penalties on any interloper. For instance, any one who sold a single stick of cinnamon in Ceylon was punished with death. When the English captured the island in 1796, all such restrictions were of course repealed. Nevertheless its cultivation remained a monopoly of the East India Company until 1832.
Logwood (Haematoxylon campechianum) is closely connected with the story of adventure and colonisation in the West Indies. Its use was at first forbidden by Queen Elizabeth as it did not yield fast colours; this was because the dyers of those times did not know of any mordant to fix them. Yet this is one of the few vegetable dyes which retain their position in the market in these days of aniline colours, and it is said to be a large constituent, with brandy, of cheap "port wine."
Indigo was known to the Romans, who imported it from India on camel-back by way of the Persian and Syrian desert. In the fifteenth century, when the Dutch began to introduce it in large quantities, it was found to interfere with the "woad"[6] (Isatis tinctoria) which was then a very important cultivated plant in Europe. In Nuremberg, an oath was administered once a year to all the manufacturers and dyers, by which they bound themselves not to use the "devil's dye," as they called Indigo. Its more recent history shows a very different system. In Assam and other parts of British India, enormous sums of money have been invested in indigo plantations. It has been estimated that four million pounds was invested, and that a population of something like 700 Europeans and 850 workmen to the square mile in Behar, were entirely supported by indigo plantations.
Now all these planters are ruined and the population is dispersed, because German indigo manufactured from coal-tar is destroying the sale of the British-grown material. The plant has pretty blue flowers and belongs to the Leguminous order. The dye is obtained by steeping the leaves and young branches in water, and it is finally turned out in blue powder or cakes.
Perhaps the most interesting of all these drugs is Pepper. The Dutch, in the days of Queen Elizabeth, had a monopoly of the East Indian trade, and they tried to cut down or burn all spice trees except those in their own control. They could thus form a corner in pepper, and alter the price as they felt inclined. At one period they doubled the price, raising it from three shillings to six shillings per pound. This annoyed the London merchants so much that they met together and formed the "Society of Merchants and Adventurers trading to the East Indies." This was of course the original source of our great East Indian trade, and later on resulted in the Indian Empire.
At present, and for centuries past, the whole world is searched and explored for drugs and spices. Our medicinal rhubarb for instance, grows in China on the frontiers of Tibet; it is carried over the mountains of China to Kiaghta in Siberia, and from thence taken right across Russian Siberia to London and New York. It is closely allied to the common or garden rhubarb, which grows wild on the banks of the Volga.
It is only our duty to remember with gratitude all those long since departed botanists who have made our life so full of luxury and have supplied our doctors with all kinds of medicines.