Question.—“Have you found the ordinary residue of the stomach from the dead poison the lower animals?”

Answer.—“I have never known it to do so. I will not say it is not so.”

Question.—“How long after the administration of aconitia would you expect the symptoms to appear?”

Answer.—“From a few minutes to an hour and a half.”

Question.—“Would the time of action depend upon the dose?”

Answer.—“The probabilities are that a large dose would soonest produce effect. The smallest dose that has produced death has been between 1-21 gr. and 1-13 gr., or about 1-16 gr.”

On re-examination by the Solicitor-General, the Witness explained that it was when corpses were putrefying that the cadaveric alkaloids were produced. He had procured alkaloidal extracts from the urine, viscera and stomach, and ascertained the effects of them upon mice: had made twenty-two experiments this year: there were two cases of heart disease, and four of the liver, kidneys, spleen, vomit, and six from the urine. He had also, in six instances, taken from the urine of living persons, and in three from that of healthy dead persons. Those extracts had no effect on his tongue. He had had many years’ experience, and certainly never tasted anything like aconitia, and he had tried these alkaloidal extracts on the same number of mice without the animals suffering except from the puncture. One of these mice, he added, he had killed with the three-thousandths of a grain, and two-thousandths of a grain was always fatal to a mouse. To a question by the judge, he said “it would make a great difference in the time when the severe symptoms appeared, whether the poison was swallowed directly and whether it came into direct contact with the tongue.” Dr. Dupré confirmed in every detail the statements of his colleague. “In his case the effects of tasting the alkaloid from the urine continued over four hours, and that from the vomit over six hours, though he took lunch and dinner during that time. In the vomit he did not find any trace of quinine which he should have expected had aconitia been given in conjunction with quinine.”

THE PREVIOUS ACTS OF THE PRISONER.

Soon after his marriage in 1879, the prisoner set up in practice at Bournemouth, whence in April, 1880, he went for a six months’ trip to America. Early in 1881, he was in great pecuniary difficulties, and had to part with his furniture to pay an execution out of his house, and again went to America on the 30th of August. Three days before he sailed, whilst staying with his mother at Ventnor, he visited Percy John at Shanklin, where the boy was staying with the Chapmans, and promised to return on the Monday, the 29th, before he left England. It was supposed that he did so, and it was then, according to the boy’s statement before reported, that he gave him a pill, after which he was taken ill in much the same way as at Blenheim House in the December following.[207] From America he returned on the 17th of October, and after a visit to Ventnor, where he got a cheque, which was subsequently dishonoured, cashed by a tradesman (Price Owen), he was in London on the 1st of December, staying at the Nelson Hotel, Portland-road. His actions are now taken up by the following witness, to whom, and to whose brother, the prisoner had from time to time advanced money, in the case of the brother pawning his surgical instruments and watch, on the 24th of November, in order to lend him five pounds.[208]