In July, 1569, difficulties began to accumulate about the printing-office in Rome. The Pope was less interested and the magistrates were troubling the office with what Paul calls unintelligent interference. There were, in fact, too many parties interested in the management of the business to enable its control to be easily or consistently exercised. Paul’s health was also failing seriously and he was longing for rest and for leisure to carry on his scholarly undertakings. In 1570, the ownership of the receipts of the printing-office was somewhat simplified, the change being probably due, in part at least, to the representations of Paul that the many-headed control was unworkable.

In May, 1570, Paul writes rather pathetically to Aldus: “In my case, scholarship and industry have never brought rest or fortune.... I pray God that you may be better favoured.... I must beseech you, however, to put away childish things. It is full time that you recalled to yourself the honourable traditions of our family.... My own active work must be nearly over.”

In June, of the same year, he again counsels Aldus, who had for some time been betrothed, to make a speedy marriage, and then to concentrate himself upon the work of the printing-office in Venice. He advises against a a plan that the young man had in view, of opening a retail book-shop. He emphasises, however, that there is no chance of success for a printer-publisher without the most persistent and arduous labour.

In 1571, Paul’s failing strength compelled him to leave Rome, resigning (as he hoped, for a time only) the income of the papal printing-office. He devoted the winter months to the completion of his Commentaries on the Orations of Cicero. The work was published in 1578-9 (after the author’s death) by his son Aldus in Venice, and, under arrangement, by Plantin in Antwerp. The negotiations with Plantin had been completed by Paul. He had specified the form and style of the Antwerp edition, and had arranged to take his share of the profits in the shape of a royalty on the sales.

In 1572, Paul being yet in Milan, one of his hopes was fulfilled in the marriage of his son Aldus. “Now,” he wrote, “I can pass my days in peace. I feel hopeful for your future and rejoice that our line is to be continued.” Later in the year, with no little difficulty (partly on the ground of his feeble health, and partly because of the floods and wretched roads) he made his way to Venice for a brief visit. He wanted to see his son’s wife, and he desired also to give personal instructions for the printing of his Commentaries. “I feel very hopeful,” he writes, “concerning the sale of my Cicero, and hopeful also that it will not be reprinted (in piracy editions) during my lifetime.”

Paul was obliged to leave Venice before the printing of his work was begun, and the letter written after the receipt of the first sheets expresses his bitter disappointment at the manner in which this all-important commission had been attended to. “If you had had in your hands some utterly contemptible scribble,” he writes, “you could hardly have printed it in a more tasteless and slovenly style ... and you knew I had this undertaking so much at heart!... I have instructed Basa to burn all the sheets that have been printed, and to print these signatures again, with a proper selection of type and on decent paper.”

Aldus the younger seems never to have had his heart fairly in his business, and under his management (or lack of management), the prestige of the Aldine Press in Venice fell off sadly. He appears to have been extravagant, or at least uncalculating, in his expenditures, and was also spending moneys which he could ill afford, not like his grandfather for manuscripts and type, but for clothes and artistic curiosities.

Paul had accepted the pressing invitation of the new Pope, Gregory XII.; to resume his place as manager of the printing-office in Rome, but with less exacting duties, and with a fixed salary. A plan was even talked over between the Pope and Paul for the establishment of another printing-office, which should be devoted entirely to the publication of classical works and of “expurgated” editions of works, portions of which had been condemned in the Index. Paul was to act as editor and supervisor of the series, because his name was already recognised as that of a scholarly authority. The scheme never, however, took shape. Paul’s strength failed rapidly, and he died in the spring of 1574.

While he had devoted many years to his business as a printer-publisher, and had maintained the reputation of his name for a high standard as well of typography as of scholarly writing, his own preference had been for a scholarly rather than a business career. He went on with the work of his Press very largely because he felt that it was a duty he owed to his father’s name and memory. His own memory is, however, chiefly to be honoured for his scholarly edition of Cicero, with its comprehensive and analytical commentaries, an edition which long remained the accepted authority for Europe.

A few years after the death of Paul, his son Aldus gave up the attempt to carry on the Press in Venice, a work for which he had never been really fitted, and accepted a position in the University of Bologna, as professor of archæology. The printing business was sold, and the Aldine Press, after a century of work, came to an end.