"Trifles light as air
Are, to the jealous mind,
Confirmations strong as proofs of Holy Writ."
Othello demands the handkerchief be produced, and repeats this several times in order to make it more effective.
The audience, or some of them at least, failed to appreciate this repetition, and grew decidedly restless.
At last, when for the third time Othello called for the handkerchief, somebody yelled out.
"Wipe yer nose on yer slaive, ye naygur, and let the play prosade."
Of course you all know that of late years a certain class of women have taken to enjoying man's attire.
Personally I don't like it.
There are some who do.