In 1834 Cabot retired to give place to Padre Jesus María Vasquez del Mercado, one of the newly arrived Franciscans from Zacatecas. In this year the neophyte population had dwindled to 567, and five years later Visitador Hartwell found only 270 living at the Mission and its adjoining ranches. It is possible, however, that there were fully as many more living at a distance of whom he gained no knowledge, as the official report for 1840 gives 500 neophytes.

Manuel Crespo was the comisionado for secularization in 1835, and he and Padre Mercado had no happy times together. Mercado made it so unpleasant that six other administrators were appointed in order to please him, but it was a vain attempt. As a consequence, the Indians felt the disturbances and discord, and became discontented and unmanageable.

In 1843, according to Governor Micheltorena's order of March 29, the temporal control of the Mission was restored to the padre. But, though the order was a kindly one, and relieved the padre from the interference of officious, meddling, inefficient, and dishonest "administrators," it was too late to effect any real service.

As far as I can learn, Pico's plan did not affect San Antonio, and it was not one of those sold by him in 1845-1846. In 1848 Padre Doroteo Ambris was in charge as curate. For thirty years he remained here, true to his calling, an entirely different kind of man from the quarrelsome, arrogant, drinking, and gambling Mercado. He finally died at San Antonio, and was buried in the Mission he guarded so well.