Strenuous and conscientious endeavor
Stretched out in dreary monotony
Strict and unalloyed veracity
Struck incessantly and remorselessly
Stupendous and awe-inspiring spectacle
Subject to the vicissitudes of fortune [vicissitudes = sudden or unexpected changes]
Subjected to the grossest cruelties
Subordination to the common weal
Subservient to the ends of religion
Sudden and inexplicable changes of mood