The commonwealth of cells

by H. G. F. Spurrell

Animals have to get their nitrogen in the form of proteid, a substance whose molecule is composed of nitrogen, oxygen, hydrogen, carbon, etc., and might roughly be described as dead protoplasm. Plants on which animals feed, when they do not get their proteid by the simpler, though less moral, method of eating one another, are able to get their nitrogen in a simpler form; but with that we are not concerned.

The proteids are a group of substances which resemble protoplasm in the elements of which they are composed and in the complexity with which they are combined. The various proteids seem, however, to have a definite chemical composition, and therefore differ from protoplasm in being true compounds; moreover, if kept from bacteria they undergo no changes. One of the best forms of proteid for examination is white of egg; this, as is known, sets or coagulates when boiled, dissolves in water, from which it may be precipitated by boiling, and displays various other chemical properties common to all proteids. There is, however, a good deal of difference between the several varieties of proteids, and the more complex ones have to be converted into the simpler before they can be absorbed. Hence the necessity for digestion.

Now, as proteid resembles dead protoplasm, it might be supposed that a diet of proteid alone would be the most economical; but this is not so. If it were possible to live without work, i.e., without movement of any kind, it might be; but to do work, more carbon must be oxidized than the proteid molecule contains.

Carbon, the next item on our list, is familiar to everyone in the comparatively pure form of coal, charcoal, and the ‘lead’ of pencils. It is commonly used to burn—i.e., oxidize—that heat may be obtained to boil water and to work machinery. This is precisely what it is required to do in the body, where it is burnt by oxygen taken in by the lungs, that heat and energy may result. It is a commonplace that severe exercise causes laboured breathing, and the reason of this is that the carbon in the body is being oxidized, and the product, carbonic acid gas, has to be got rid of. The more work is being done, the more oxygen is required to burn carbon in the muscles. The more carbon is burnt, the more heat is evolved, and the more necessary it is that the blood should be cooled by drawing cool air into the lungs. Hence the more rapid breathing. The air normally breathed out is always warmer than that taken in, and always contains extra carbonic acid gas. After exercise the quantity is increased, and its increase on the normal amount given off can readily be demonstrated by analyzing samples of the air taken in and given out.

But carbon, like nitrogen, cannot be taken in in the crude form. No one would try to make a meal of charcoal. A certain amount is contained in the proteid molecule, enough, no doubt, to secure the basis of the protoplasmic structure; but unless one is prepared to eat an excessive quantity of proteid, a proceeding entailing waste and exhaustion of the digestive apparatus, the balance must be made up by eating carbohydrate.

The forms in which people are most familiar with carbohydrate are starch and sugar. Sugar is the better food, as it is so much more soluble than starch; and, in fact, starch is always turned into a kind of sugar before it is used by the body. The common cane-sugar, which everyone knows so well, is about the most useful food we have, owing to its purity, and therefore concentration, and its simplicity. A very small amount of digestion is necessary to convert it into the simplest of all carbohydrates, a substance easily stored, as glycogen, till wanted, which is present in muscle after a meal, and is used up when the muscle is active, being oxidized to carbonic acid gas, sarcolactic acid, and alcohol.

The importance of carbon in the diet is therefore obvious; and people who intend doing extra muscular work should take extra sugary food rather than extra proteid. A locomotive which is about to make a record run takes in more coal, not more engine-drivers, and our athletes now follow the same principle. We shall, however, have a good deal more to say about athletes presently.

There is yet another point to be considered in respect to carbon. Carbon need not be taken in the form of carbohydrate, the alternative being fats and oils. Fats and carbohydrates are both composed of the elements carbon, hydrogen, and oxygen, but the proportions in which they are joined are different. Fats are not such useful foods as carbohydrates, nor to most people so pleasant—compare a spoonful of olive-oil and a lump of sugar. But there is one important point to be urged in their favour: they yield twice as much heat as either proteids or carbohydrates; so their position among foods is assured.

The other chemical necessities of the body we need only mention here. Hydrogen is one of the components of proteid, carbohydrate, fat, and water; and if it does not enter in the last form, it—at any rate, most of it—leaves as such, being oxidized in the tissues. Sulphur and iron deserve honourable mention; common salt is required by the blood; lime and phosphates go to make bone; but important as they all are, they need not detain us further at present.

With regard to the amount of these elements which is required per day, and which is ascertained by collecting and weighing all that is given off, it is found that about ½ ounce of nitrogen and 10 ounces of carbon are necessary to an average man—i.e., weighing about 10 stone. The ½ ounce of nitrogen and about 2 ounces of the carbon are contained in 4 ounces of dry proteid, which leaves a balance of 8 ounces of carbon to be made up; and this is usually obtained by eating 4 ounces of fat and 18 ounces of carbohydrate.