3. Partial paralysis of the œsophagus, not spasmodic stricture; but sluggish and incomplete contraction of the muscles of deglutition, with regard to both food and drink. This was well marked in Case 2, and in both recurred at intervals for many months; even after convalescence was established.

4. Dimness of sight; eyes bloodshot and constantly watering. Once, after total cessation of chloral, temporary loss of vision, lasting, with intervals, two days.

5. Dryness of the hair.

Case 2.—Lady, aged forty-five, good health and keen intellect. Insomnia from worry and from dyspepsia. Had taken chloral for two years. At first only at bedtime; after a time during the day also. Never above seventy grains in twenty-four hours. Both physical and mental exhaustion, morbid fear, confusion of mind, lack of concentration and impairment of memory. (She was, however, an authoress, apparently doing her regular literary work.—K.)

POINTS OF INTEREST.

1. Erythema of head and neck.

2. Excessive hyperæmia after smallest quantity of wine or beer.

3. Partial paralysis of the œsophagus, with nervous disinclination to take food or drink.

4. Dimness of sight, with eyes bloodshot and overflowing with tears. Marked projection of eyeballs.

5. Intense nausea, oftentimes, after taking chloral.