More recent experiments by Brumpt have shown that young sucking pigs can be infected with Balantidium from infected monkeys (Macacus cynomolgus) and suffer heavily from the same, whereas the Balantidium of the pig is rarely harmful to its host. This and previous experiments may be thought to suggest that there are perhaps several pathogenic species, and also that harmless strains of Balantidium may occur. At the same time, it must be remembered that a large proportion of the cases recorded of Balantidian colitis occur among swineherds and butchers, that is, among people in frequent contact with pigs. Morphologically, there are practically no differences between the Balantidia found in man, monkeys and pigs, and it is probable that one species only, under slightly different environmental conditions, may be responsible for the colitis observed. In any case, efficient prophylactic measures should be taken against balantidiasis in countries where it may occur, by confining the pigs and not allowing them to run in yards and dwellings.
E. L. Walker (1913) has given a good summary of work on balantidiasis. His own researches in the Philippines showed that monkeys could be infected by Balantidia both from pigs and men. Parasites may appear in the stools only at infrequent intervals. He believes that the ciliates are the primary etiologic factor in the symptoms and lesions of balantidian dysentery.
Behrenroth (1913) has given an interesting account of Balantidium coli and its pathogenic significance.
Balantidium minutum, Schaudinn, 1899.
Fig. 115.—Balantidium minutum. P, peristome; N, nucleus; M, micronucleus; V, contractile vacuole. Food vacuoles are represented in the endoplasm. (After Schaudinn.)
The body is of oval form, with the anterior extremity pointed, and posterior extremity broad and rounded (fig. 115). The length is 20 µ to 32 µ, and the breadth is 14 µ to 20 µ. The peristome, which is fissure-like, extends to the centre of the body (fig. 115). The right lateral border of the peristome is beset with cilia the same length as those of the body, the left side terminates in a thin hyaline membrane that extends towards the back, and can pass over to the right side. A row of longer and stronger cilia (cirri) are on the left border of the peristome. The cuticle is refractile, the ectoplasm hyaline and the endoplasm granular, with numerous food vacuoles.
A single contractile vacuole lies dorsally and to one side at the posterior extremity. The macronucleus, which is always spherical, is central and is 6 µ to 7 µ in diameter. The micronucleus, close in front of it, only measures 1 µ (fig. 115). The cysts are oval.
These parasites were found in numbers in the evacuations of a man aged 30, who was born in Germany and had repeatedly travelled between Hamburg and North America, where he made long stays. The patient came to the Charité in Berlin to seek advice for constipation alternating with diarrhœa accompanied by abdominal pain.