She fell upon exciting times in Italy. There had grown up the fiercest hatred of the Austrian rule, which had recently been aggravated by foolish acts of repression and violence. The whole country was in a ferment. Mazzini, whom Margaret had met in London, was here awaiting his opportunity. Mrs. Howe says: "Up and down went the hopes and the hearts of the Liberal party. Hither and thither ran the tides of popular affection, suspicion, and resentment. The Pope was the idol of the moment. The Grand Duke of Tuscany yielded to pressure whenever it became severe. The minor princes, who had from their birth been incapable of an idea, tried as well as they could to put on some semblance of concession without really yielding anything." Margaret was soon in close relations with leading Liberals, and shared all their hopes and fears and some of their dangers.
At this time she first met the young Italian nobleman, Ossoli, who became her husband. She became separated from her party one day at some service at St. Peter's, and, wandering around trying to find them, became tired and somewhat agitated. A young man of gentlemanly address offered his services to her as guide; and after looking in vain for her friends, she was obliged to accept his escort home, night having come on and no carriages being in attendance. They became mutually attracted, and the acquaintance continued, with that disregard of conventionality for which American women are noted when abroad. Although much younger than Margaret, he seemed to be greatly interested in her; and although he had none of her intellectual tastes, she was equally interested in him.
A very romantic attachment sprang up between them, which ended after a few months in a secret marriage. Her reason for the secrecy lay in the troubled times, and the fear of Ossoli's being deprived of his paternal inheritance on account of marrying a Protestant. They had great hopes of the coming revolution, and trusted to a more liberal government to give him his rights despite the fact of his marrying outside the Church of Rome. He was as poor as Margaret herself; and this was another reason for living apart for a time. He was a captain in the Civic Guard, and at this time much occupied with military duties. It was at this time that the Roman Republic was proclaimed, with great pomp of rejoicing; and Margaret chronicles the opening of the Constitutional Assembly, with great display of processions and banners. In one procession walked a Napoleonic prince side by side with Garibaldi, both having been chosen as deputies. All this raised the hopes of the Liberals throughout Europe to the highest point, and Margaret was almost transported with happy excitement,—probably not understanding as well as the natives of Italy how ill prepared that country was for liberty, and how soon the despotic power would again close around the people. In point of fact, the Republic lasted but a few days, and Margaret's brief time for rejoicing was over, and her own personal troubles became very urgent and oppressive.
A son had been born to her some months before, and had of necessity been left in the hands of a nurse in the country, as the marriage had not yet been made known. During all the pomp of processions and the ringing of bells and firing of cannon, she had heard the voice of her infant crying at Rieti. She had not seen him for three months, on account of the troublous times. She lay awake whole nights contriving how she might end the separation which seemed killing her; but circumstances were too strong for her, and the object so dear to her heart could not be compassed. The French were already in Italy. The siege of Rome soon ended in the downfall of the Republic, and the government was placed in the hands of a triumvirate. The city once invested, military hospitals became a necessity. Margaret was named superintendent of the hospital of the Fate Bene Fratelli. "Night and day," writes Mrs. Story, "Margaret was occupied, and with the Princess Belgiojoso so ordered and disposed the hospitals that their conduct was admirable. Of money they had very little, and they were obliged to give their time and thoughts in its place. I have walked through the wards with Margaret, and have seen how comforting was her presence to the poor suffering men. For each one's peculiar taste she had a care. To one she carried books; to another she told the news of the day; and listened to another's oft-repeated tale of wrongs, as the best sympathy she could give. They raised themselves on their elbows to get a last glimpse of her as she went away." Ossoli was stationed with his command on the walls of the Vatican, and in great danger. He refused to leave his post even for food and rest. The provisions which Margaret sent him he shared with his comrades. Sometimes she could visit him at his post and talk about the little Angelo, now always in her thoughts. As the wounded men were brought into the hospital she was always expecting to see her husband; and as the nurse had threatened to abandon the babe, and it was utterly impossible for Margaret to get outside the lines now investing the city, the two horrors were almost more than she could bear. It was only in trying to help the helpless that she found any consolation in this dreadful time. The night of the 20th of June, the French effected an entrance into the city; and although the defence was gallantly continued until the 30th, there was really no hope for the patriots.
At that time Garibaldi informed the Assembly that further resistance would be useless. The French occupation then began, and the end of all liberties. The gates once open, Margaret, with all her sorrow for Rome, was happy in the thought of reaching her child. She did reach him just in time to save his life. He had been forsaken by his nurse, and his mother found him "worn to a skeleton, too weak to smile or lift his wasted little hand." All that Margaret had endured seemed slight compared to this. She could but compare the women of the Papal States to wolves. The child, however, recovered with good nursing, and the family, now united, enjoyed a little season of repose and happiness. The marriage was announced, and Margaret's many friends in Rome extended their help and sympathy. Life in Italy had now become so painful to them that she resolved to return to the New World. Her husband was willing to accompany her. They accordingly engaged passage upon a merchant-vessel from Leghorn, the same vessel being engaged to bring over the heavy marble of Powers's "Greek Slave." She seemed to have great forebodings about this voyage, and was almost induced to give up their passage on the vessel at the last moment; but she overcame her fears, and they embarked. After a few days the captain died of small-pox. The disease spread; and Margaret, as courageously as ever, went about the ship nursing the sick. Soon the little Angelo was taken with the dread disease; they nursed him safely through it, however, and after many dangers and trials the vessel arrived off the Jersey coast in thick weather. At night, the mate promised them a landing in New York in the morning; but the vessel ran upon the sand-bars near Long Island, and on Fire Island beach she struck at four o'clock on the morning of July 19. Margaret, with husband and child, was lost, after refusing to be separated in the efforts at rescue. They went down together, and the career of a great and noble woman ended thus tragically on that desolate coast.