Early in the year 1862 the Indians made continuous raids on the coaches and stations between Fort Laramie and the South Pass. In April of that year a terrible battle occurred between the mail-stage and the Indians on the Sweetwater River near Split Rock, or Devil's Creek. The white party consisted of nine men with two coaches loaded with mail. They were in charge of Lem Flowers, the division agent, and Jimmie Brown, the conductor. The Indians began the attack at early dawn and the white men were so harassed that they were compelled to run the two coaches alongside of each other, pile the mail-sacks between the wheels, and throw sand over them for breastworks. From this barricade they fought the savages the whole day, but they lost all the stock, and six of the men were wounded. Several Indians were killed during the fight, and when night came on they withdrew. Under cover of the darkness the men took the front wheels of the running-gear of the coaches, put the wounded upon them, and, drawing it themselves, made their escape to the station of the Three Crossings of the Sweetwater River.

One of the employees who passed over the route shortly after the fight and visited the scene of the battle in company with the notorious Slade, who was then division agent, says: “The coaches were still standing as they were placed by the party in the fight, completely riddled with bullets and arrows. Every vestige of leather straps and cushions was stripped off, the mail-sacks cut open, their contents thrown out, and the sacks themselves carried off. Valuable letters, drafts, and bills for large amounts were scattered all over the ground. This mail was gathered up by the employees, put in gunny sacks, hauled to Julesburg, and from there forwarded to the Post-Office Department at Washington.”

Another memorable raid was made by the savages on the old line mail-route on Sunday, the 7th of August, 1864. It was a simultaneous attack on that portion of the line extending over two hundred miles from Julesburg eastwardly to Liberty Farm, at the head of the Little Blue River. The mail-coaches, the stations, travelling freight caravans, ranches, and parties putting up hay were alike attacked. Forty people were killed, many ranches and trains burned, much stock and other property stolen and destroyed in that eventful raid.

At last the raids of the savages along the North Platte had become so frequent, and the duty so hazardous, that it was almost impossible for the Overland Stage Company to find drivers, although the highest wages were offered. At this juncture W. F. Cody decided to turn stage-driver and his services were gladly accepted.

While driving a stage between Split Rock and Three Crossings, he was set upon by a band of several hundred Sioux. Lieutenant Flowers, assistant division agent, sat on the box beside Cody, and there were half a dozen passengers well armed inside. Cody gave the reins to Flowers, applied the whip, and the passengers defended the stage in a running fight. Arrows fell around and struck the stage like hail, wounding the horses and dealing destruction generally, for two of the passengers were killed and Flowers badly wounded. Cody seized the whip from the wounded officer, applied it savagely, shouting defiance, and drove on to Three Crossings, thus saving the stage.

The only period when the long route up the Platte Valley enjoyed an immunity from the continuous trouble with the savages, before the completion of the Union Pacific Railroad, was when General Albert Sidney Johnston's army, in 1857, had been mobilized for the impending Mormon war. More than five thousand regular soldiers, with its large commissary trains and their complement of teamsters, all well armed, together with batteries of artillery, in passing through the country so intimidated the Indians, who had never before seen such an array of their enemies, that they remained at a respectful distance from the trail.

In the spring of 1865 the Indians seemed more determined than ever to wage a relentless war along the line of the Overland Stage.

A regular army officer in his journal says:—

During the time when we were guarding Ben Holliday's stage-coaches, and when attacks on them were of frequent occurrence, I had an adventure which I think is worth relating.

I was out at one of the lower ranches, and the Indians were very troublesome. Our guards were nearly all sick or wounded, and the coaches had to go out insufficiently protected.