To this work succeeded, in 1543, the Homilies of Saint Chrysostom, of which John Cheke, Professor in Greek at Cambridge University, was editor. The whole of the first part of the work, with the exception of the dedication, was in Greek letter, making thirty lines to the quarto page. The second part, which had a separate title-page, was printed with the Italic, and the supplementary parts with the Roman types. Some very fine pictorial initial letters were used throughout the work, and the larger form of the apple-tree device occurs on the last leaf, with a Greek and Latin motto.

A very rare specimen of Wolfe's work in 1543 is Robert Recorde's The groūd of artes teachyng the worke and practise of Arithmetike moch necessary for all states of men, a small octavo printed in black letter, but of no particular merit. In the same type and form he issued in the following year a tract entitled The late expedicion in Scotlande, etc. Chrysostom's De Providentia Dei and Laudatio Pacis were printed in the Roman and Italic founts during 1545 and 1546, and are the only record we have left of Wolfe's work as a printer during those years. In 1547 he was appointed the king's printer in Latin, Greek, and Hebrew, and was granted an annuity of twenty-six shillings and eightpence during his life (Pat. Rol. 19 April 1547).

In 1553 trouble arose between Wolfe and Day as to their respective rights of printing Edward the Sixth's catechism. The matter was settled by Wolfe having the privilege for printing the Latin version, and Day that in English, but neither party reaped much benefit, as upon the king's death the book was called in, having only been in circulation a few months. During Mary's reign the only important work that seems to have come from Wolfe's press was Recorde's Castle of Knowledge, a folio, with an elaborately designed title-page, and a dedication to Cardinal Pole. In 1560 Wolfe became Master of the Company of Stationers, a position to which he was elected on three subsequent occasions, in 1564, 1567, and 1572. His patents were renewed to him under Elizabeth, and he came in for his share of the patronage of Matthew Parker, whose edition of Jewel's Apologia he printed in quarto form in 1562. In 1563 appeared from his press the Commonplaces of Scripture, by Wolfgang Musculus, a folio, chiefly notable for a very fine pictorial initial 'I,' measuring nearly 3-1/2 inches square, and representing the Creation, which had obviously formed part of the opening chapter of Genesis in some early edition of the Bible. It was certainly used again in the 1577 edition of Holinshed's Chronicle.

Almost his last work was Matthew Paris's Historia Major, edited by Matthew Parker, a handsome folio with an engraved title-page, several good pictorial initials, and his large device of the apple-tree, printed in 1571. Without doubt the printer was greatly interested in this work. He had himself collected materials for a chronicle of his adopted country, which he amused himself with in his spare time. But he did not live to print it, his death taking place late in the year 1573. His will was short, and mentioned none of his children by name. His property in St. Paul's Churchyard, which included the Chapel or Charnel House on the north side, which he had purchased of King Henry VIII., he left to his wife, and the witnesses to his will were George Bishop, Raphael Holinshed, John Hunn, and John Shepparde.[6] His wife, Joan Wolfe, only survived him a few months, her will, which is also preserved in the Prerogative Court of Canterbury,[7] being proved on the 20th July 1574. In it occurs the following passage:

'I will that Raphell Hollingshed shall have and enjoye all such benefit, proffit, and commoditie as was promised unto him by my said late husbande Reginald Wolfe, for or concerning the translating and prynting of a certain crownacle which my said husband before his decease did prepare and intende to have prynted.'

She further mentioned in her will a son Robert, a son Henry, and a daughter Mary, the wife of John Harrison, citizen and stationer, as well as Luke Harrison, a citizen and stationer, while among the witnesses to it was Gabriel Cawood, the son of John Cawood, who lived hard by at the sign of the Holy Ghost, next to 'Powles Gate.'

From a document in the Heralds' College (W. Grafton, vi., A. B. C., Lond.), it appears that John Cawood, who began to print about the same time as Day, came from a Yorkshire family of good standing. He was apprenticed to John Reynes, a bookseller and bookbinder, who at that time, about 1542, worked at the George Inn in this locality. Cawood greatly respected his master, and in aftertimes, when he had become a prosperous man, placed a window in Stationers' Hall to the memory of John Reynes. Reynes died in 1543, but there is no mention of Cawood in his will, perhaps because Cawood was no longer in his service; but in that of his widow, Lucy Reynes, there was a legacy to John Cawood's daughter.

Cawood began to print in the year 1546, the first specimen of his press work being a little octavo, entitled The Decree for Tythes to be payed in the Citye of London.

With few exceptions the printers of this period easily enough conformed to the religious factions of the day. Thus Cawood prints Protestant books under Edward VI., Catholic books under Mary, and again Protestant books under Elizabeth. Upon the accession of Mary he was appointed royal printer in the place of Grafton, who had dared to print the proclamation of Lady Jane Grey (Rymer's Fœdera, vol. xv., p. 125). He also received the reversion of Wolfe's patent for printing Latin, Greek, and Hebrew books, as well as all statute books, acts, proclamations, and other official documents, with a salary of £6, 13s. 4d. The British Museum possesses a volume (505. g. 14) containing the statutes of the reign of Queen Mary, printed in small folio by Cawood. From these it will be seen that he used some very artistic woodcut borders for his title-pages, notably one with bacchanalian figures in the lower panel signed 'A. S.' in monogram, evidently the same artist that cut the woodcut initials seen in these and other books printed by this printer, and who is believed to have been Anton Sylvius, an Antwerp engraver. Cawood was one of the first wardens of the Stationers' Company in 1554, and again served from 1555-7, and continued to take great interest in its welfare throughout his life. In 1557, Cawood, in company with John Waley and Richard Tottell, published the Works of Sir Thomas More in a large and handsome folio. The editor was William Rastell, Chief Justice of the Queen's Bench, son of John Rastell the printer, and nephew of the great chancellor.

The book was printed at the Hand and Star in Fleet Street by Tottell, but the woodcut initials were certainly supplied by Cawood, and perhaps some of the type. On the accession of Elizabeth, he again received a patent as royal printer, but jointly with Richard Jugge, whose name is always found first. Nevertheless, Cawood printed at least two editions of the Bible in quarto, with his name alone on the title-page. They were very poor productions, the text being printed in the diminutive semi-gothic type that had done duty since the days of Caxton, and the woodcut borders being made up of odds and ends that happened to be handy. His rapidly increasing business had already compelled him to lease from the Dean and Chapter of St. Paul's a vault under the churchyard, and two sheds adjoining the church, and in addition to this he now took a room at Stationers' Hall at a rental of 20s. per year.