Give the constitutional treatment of the late, or localized, syphilodermata.
Mercury always, usually in small or moderate dosage, as the biniodide or corrosive chloride, and potassium iodide; the latter in dose varying from two grains to two drachms or more, t.d., depending upon its action and the urgency of the case.
How long is constitutional treatment to be continued in cases of the late syphilodermata?
Actively for several weeks after the disappearance of all symptoms, and then (especially the mercury) continued in smaller dosage (about one-third) for several months longer.
What applications are usually advised in the late, or localized, syphilodermata?
Ointment of ammoniated mercury, twenty to sixty grains to the ounce; oleate of mercury, five to ten per cent. strength; mercurial plaster, full strength or weakened with lard or petrolatum; a two to twenty per cent. ointment of iodol; resorcin, twenty to sixty grains to the ounce of ointment base; and lotions of corrosive sublimate, one-half to three grains to the ounce.
The following is valuable in offensive and obstinate ulcerations:—
℞ Hydrarg. chlorid. corros., ....................... gr. iv-gr. viij
Ac. carbolici, ................................... gr. x-xx
Alcoholis, ...................................... fʒiv
Glycerinæ, ...................................... fʒj
Aquæ, ................ q.s. ad. .................. ℥iv. M.
Ointments are to be rubbed in or applied as a plaster; lotions, employed chiefly in ulcers and ulcerations, are to be thoroughly dabbed on, and usually supplemented by the application of an ointment. Iodol may also be applied to ulcers as a dusting-powder, usually mixed with one to several parts of zinc oxide or boric acid.
Give the treatment of hereditary infantile syphilis.