As I now look back upon it, the worst of the experiment lay in the three weeks intervening between the 10th and the 31st of December. So far as mere pain of body was concerned, there was little to choose between the agony of one day and another; but the apprehension that insanity might set in, certainly aggravated the distress of the later stages of the trial. When a man knows that he is practicing self-control to the very utmost, and holding himself up steadily to his work in spite of the gravest discouragements, the consciousness that a large vacuum is being gradually formed in his brain is not exhilarating.

The next day—to me a very memorable one—the fourth of January, I sat for most of the day rocking backward and forward on a sofa or a chair, speaking occasionally a few words in a low sepulchral voice, but with the one bitter feeling, penetrating my whole nature, that come what would, on that day I would not.

When the clock struck twelve at midnight, and I knew that for the first time in many years I had lived for an entire day without opium, it excited no surprise or exultation. The capacity for an emotion of any kind was exhausted. I seemed as little capable of a sentiment as a man well could be, this side of his winding-sheet. I knew, of course, that in these forty days save one, I had worked out the problem, How to leave off opium, and that I had apparently attained a final deliverance: but it was several weeks before I appreciated with any confidence the completion of the task I had undertaken.

Although the opium habit was broken, it was only to leave me in a condition of much feebleness and suffering. I could not sleep, I could not sit quietly, I could not lie in any one posture for many minutes together. The nervous system was thoroughly deranged. Weak as I had become, I felt a continual desire to walk. The weather was unfavorable, but I managed to get several miles of exercise almost daily. But this relief was limited to four or five hours at most, and left the remainder of the day a weary weight upon my hands. The aversion to reading had become such that some months elapsed before I took up a book with any pleasure. Even the daily papers were more than I could well fix my attention upon, except in the briefest and most cursory way. Within a week, however, the sense of acute pain rapidly diminished, but the irritability, impatience, and incapacity to do any thing long remained unrelieved. The disordered liver became apparently more disordered with the progress of time, producing such effects upon the bowels as may with more fitness be told a physician than recorded here. The tonsils of the throat were swollen, the throat itself inflamed, while the chest was penetrated with what seemed like pulsations of prickly heat. There was also a sense of fullness in the muscles of the arms and legs which seemed to be permeated, if I may so express it, with heated electricity. The general condition of the nervous system will be sufficiently indicated by the statement that it was between three or four months before I could hold a pen with any degree of steadiness. Meantime, singular as it may seem, the appearance of health and vigor had astonishingly increased. I had gained more than twenty pounds in weight, partly, I suppose, the result of leaving off opium and tobacco, and partly the consequence of the insatiable appetite with which I was constantly followed. Within a month after the close of the opium strife, I was repeatedly congratulated upon my healthy, vigorous condition. Few men in the entire city bore about them more of the appearance of perfect health, and fewer still were probably in such a state of exhausted vitality.

During the time I was leaving off opium I had labored under the impression that the habit once mastered, a speedy restoration to health would follow. I was by no means prepared, therefore, for the almost inappreciable gain in the weeks which succeeded, and in some anxiety consulted a number of physicians, who each suggested in a timid way the trial, some of strychnine, some of valerian, some of lupuline, hyoscyamus, ignatia, belladonna, and what not. I do not know that I derived the slightest benefit from any of these prescriptions, or from any other therapeutic agency, unless I except the good effects for a few days of bitters, and of cold shower-baths from a tank in which ice was floating.

The most judicious of the medical gentlemen whose aid I invoked, was, I think, the one who replied to my inquiry for his bill, "What for? I have done you no good, and have learned more from you than you have from me."

This constitutes the entire history of my medical experience, and is mentioned as being the only, and a very small adjunct to the great remedy—patient, persistent, obstinate endurance. So exceeding slow has been the process toward the restoration of a natural condition of the system, that writing now, at the expiration of more than a year since opium was finally abandoned, it seems to me very uncertain when, if ever, this result will be reached. Between four and five months elapsed before I was at all capable of commanding my attention or controlling the nervous impatience of mind and body. I then assented to a proposal which involved the necessity of a good deal of steady work, in the hope that constant occupation would divert the attention from the nervousness under which I suffered and would restore the self-reliance which had so long failed me. It was a foolish experiment, and might have proved a fatal one. The business I had undertaken required a clear head and average health, and I had neither. The sleep was short and imperfect, rarely exceeding two or three hours. The chest was in a constant heat and very sore, while the previous bilious difficulties seemed in no way overcome. The mouth was parched, the tongue swollen, and a low fever seemed to have taken entire possession of the system, with special and peculiar exasperations in the muscles of the arms and legs.

The difficulty of thinking to any purpose was only equalled by the reluctance with which I could bring myself to the task of holding a pen. For a few weeks, however, the necessity of not wholly disgracing myself forced me on after a poor fashion; but at the end of two months I was a used-up man. I would sit for hours looking listlessly upon a sheet of paper, helpless of originating an idea upon the commonest of subjects, and with a prevailing sensation of owning a large emptiness in the brain, which seemed chiefly filled with a stupid wonder when all this would end.

More than an entire year has now passed, in which I have done little else than to put the preceding details into shape from brief memoranda made at the time of the experiment. While the physical agony ceased almost immediately after the opium was abandoned, the irritation of the system still continues. I do not know how better to describe my present state than by the use of language which professional men may regard as neither scientific nor accurate, but which will express, I hope, to unprofessional readers the idea I wish to convey, when I say that the entire system seems to me not merely to have been poisoned, but saturated with poison. Had some virus been transfused into the blood, which carried with it to every nerve of sensation a sense of painful, exasperating unnaturalness, the feeling would not, I imagine, be unlike what I am endeavoring to indicate.

ADDENDA.—At the time of writing the preceding narrative I had supposed that the entire story was told, and that the intelligent reader, should this record ever see the light, would naturally infer, as I myself imagined would be the case, that the unnatural condition of the body would soon become changed into a state of average health. In this I was mistaken. So tenacious and obstinate in its hold upon its victim is the opium disease, that even after the lapse of ten years its poisonous agency is still felt. Without some reference to these remoter consequences of the hasty abandonment of confirmed habits of opium-eating, the chief object of this narrative as a guide to others (who will certainly need all the information on the subject that can be given them) would fail of being secured. While unquestionably the heaviest part of the suffering resulting from such a change of habit belongs to the few weeks in which the patient is abandoning opium, it ought not to be concealed that this brief period by no means comprises the limit within which he will find himself obliged to maintain the most rigid watch over himself, lest the feeling of desperation which at times assaults him from the hope of immediate physical restoration disappointed and indefinitely postponed, should drive him back to his old habits. Indeed, with some temperaments, the greatest danger of a relapse comes in, not during the process of abandonment, but after the habit has been broken. Great bodily pain serves only to rouse up some natures to a more earnest strife, and, as their sufferings become more intense, the determination not to yield gains an unnatural strength. The mind is vindicating itself as the master of the body. While in this state, tortures and the fagot are powerless to extort groans or confessions from the racked or half-consumed martyr. Many a sufferer has borne the agony of the boots or the thumb-screw without flinching, whose courage has given way under the less painful but more unendurable punishment of prolonged imprisonment. In the one case all a man's powers of resistance are roused; he feels that his manhood is at stake, and he endures as men will endure when they see that the question how far they are their own masters, is at issue. There are, I think, a great number of men and women who would go unflinchingly to the stake in vindication of a principle, whose resolution, somewhere in the course of a long, solitary, and indefinite imprisonment, would break down into a discreditable compromise of opinions for which they were unquestionably willing to die.