But of all the maladies that affect cutaneous transpiration, diapedesis, or sweating of blood, is the most singular; so much so, indeed, that its existence has been doubted, although several well authenticated cases are on record, both in the ancient and modern annals of medicine. It is mentioned by Theophrastus and Aristotle, while Lucan thus describes it:
Sic omnia membra
Emisere simul rutilum pro sanguine virus.
Sanguis erant lacrymæ; quacumque foramina novit
Humor, ab his largus manat cruor: ora redundant,
Et patulæ nares; sudor rubet; omnia plenis
Membra fluunt venis: totum est pro vulnere corpus.
The detestable Charles IX. of France sunk under this disorder, thus described by Mezeray: “La nature fit d’étranges efforts pendant les deux dernières semaines de la vie de ce Roi. Il s’agitait et se remuait sans cesse; le sang lui rejalliait par les pores et par tous les conduits de son corps. Après avoir longtems souffert, il tomba dans une extrème faiblesse et rendit l’ame.” The same historian relates the case of a governor of a town taken by storm, who was condemned to die, but was seized with a profuse sweating of blood the moment he beheld the scaffold. Lombard mentions a general who was affected in a similar manner on losing a battle. The same writer tells us of a nun who was so terrified when falling into the hands of a ruthless banditti, that blood oozed from every pore. Henry ab Heer records the case of a man who not only laboured under diapedesis, but small worms accompanied the bloody secretion.
In the Memoirs of the Society of Arts of Haarlem, we read of the case of a sailor, who, falling down during a storm, was raised from the deck streaming with blood. At first it was supposed that he had been wounded, but, on close examination, the blood was found to flow from the surface of the body. Fabricius de Hilden mentions a case that came under the observation of his friend Sporlinus, a physician of Bâle; the patient was a child of twelve years of age, who never drank any thing but water: having gone out into the fields to bring home his father’s flocks, he stopped upon the road, and contrary to habit, drank freely of white wine. He shortly after was seized with fever. His gums first began to bleed, and soon after an hæmorrhage broke out from every part of the integuments, and from the nose. On the eighth day of the malady he was in a state of extreme debility, and the body was covered with livid and purple spots, while every part from whence the blood had exuded was stopped with clots. A case is also related of a widow of forty-five years of age, who had lost her only son. She one day fancied that she beheld his apparition beseeching her to relieve him from purgatory by her prayers, and by fasting every Friday. The following Friday, in the month of August, a perspiration tinged with blood broke out. For five successive Fridays the same phenomenon appeared, when a confirmed diapedesis appeared. The blood escaped from the upper part of the body, the back of the head, the temples, the eyes, nose, the breast, and the tips of the fingers. The disorder disappeared spontaneously on Friday the 8th of March of the following year. This affection was evidently occasioned by superstitious fears; and this appears the more probable from the periodicity of the attacks. The first invasion of the disease might have been purely accidental; but the regularity of its subsequent appearance on the stated day of the vision may be attributed to the influence of apprehension. Bartholinus mentions cases of bloody sweat taking place during vehement terror and the agonies of torture.
The case of Catherine Merlin, of Chamberg, is well authenticated, and worthy of being recorded. She was a woman of forty-six years of age, strong and hale. She received a kick from a bullock in the epigastric region, that was followed by vomiting of blood: this discharge having been suddenly stopped by her medical attendants, the blood made its way through the pores of various parts of her body, every limb being affected in turn. The sanguineous discharge was invariably preceded by a prickly and itching sensation; frequently this itching exudation proceeded from the scalp. The discharge usually occurred twice in the twenty-four hours; and on pressing the skin, the flow of blood could be accelerated and increased.
Dr. Fournier relates the case of a magistrate who was attacked with diapedesis after any excitement, whether of a pleasurable or a painful nature.
A singular idiosyncrasy was transmitted to her male children by an American Female named Smith, occasioning a severe hæmorrhage wherever the skin was slightly pricked or scratched. This loss of blood would sometimes continue for several days. Several of her sons sunk under the affection, which was found at last to yield to the sulphate of soda. What is most singular, all her daughters were exempted from this fearful predisposition.
It is probable that this strange disorder arises from a violent commotion of the nervous system, turning the streams of blood out of their natural course, and forcing the red particles into the cutaneous excretories. A mere relaxation of the fibres could not produce so powerful a revulsion. It may also arise in cases of extreme debility in connexion with a thinner condition of the blood.
Curious cases are recorded of a sandy sweat, in which the perspiration becomes crystallized on the surface of the skin. Bartholinus, Schunig, and Mollenbroek have related several cases of the kind. It is probable, as Mason Good observes, that this morbid secretion may arise from an excess of uric acid, translated from the kidneys to the skin; this sand is generally of the same red colour as that of the renal secretions deposited in a lateritious sediment.
Scented perspiration is another singular peculiarity. This odour, frequently unpleasant, has also been known to shed an agreeable aroma, compared to the perfume of violets, roses, and musk. This quality is common in various animals; in the Simia jacchus, hedgehogs, hares, serpents, and crocodiles. The Viverra zibetha and V. civetta yield this odour abundantly; and it has been observed in a faint degree in our domestic cat. Many insects exhale an agreeable odour; especially the Cerambix moschatus, the Apis fragrans, the Tipula mochifera. The Cerambix suaveolens emits a delicious smell of roses, and the Petiolated sphex a highly fragrant balsamic ether. In the Memoirs of the Queen of Navarre, we read that Catherine de Medicis was a perfect nosegay; and Cujacius and Lord Herbert of Cherbury were equally distinguished by the suavity of their transpiration.