It results from the simplest methods of interpretation, that leaving out of view certain patches of metamorphosed rocks, and certain volcanic products, all that is now dry land has once been at the bottom of the waters. It is perfectly certain that, at a comparatively recent period of the world's history—the Cretaceous epoch—none of the great physical features which at present mark the surface of the globe existed. It is certain that the Rocky Mountains were not. It is certain that the Himalaya Mountains were not. It is certain that the Alps and the Pyrenees had no existence. The evidence is of the plainest possible character, and is simply this:—We find raised up on the flanks of these mountains, elevated by the forces of upheaval which have given rise to them, masses of Cretaceous rock which formed the bottom of the sea before those mountains existed. It is therefore clear that the elevatory forces which gave rise to the mountains operated subsequently to the Cretaceous epoch; and that the mountains themselves are largely made up of the materials deposited in the sea which once occupied their place. As we go back in time, we meet with constant alternations of sea and land, of estuary and open ocean; and, in correspondence with these alternations, we observe the changes in the fauna and flora to which I have referred.
But the inspection of these changes gives us no right to believe that there has been any discontinuity in natural processes. There is no trace of general cataclysms, of universal deluges, or sudden destructions of a whole fauna or flora. The appearances which were formerly interpreted in that way have all been shown to be delusive, as our knowledge has increased and as the blanks which formerly appeared to exist between the different formations have been filled up. That there is no absolute break between formation and formation, that there has been no sudden disappearance of all the forms of life and replacement of them by others, but that changes have gone on slowly and gradually, that one type has died out and another has taken its place, and that thus, by insensible degrees, one fauna has been replaced by another, are conclusions strengthened by constantly increasing evidence. So that within the whole of the immense period indicated by the fossiliferous stratified rocks, there is assuredly not the slightest proof of any break in the uniformity of Nature's operations, no indication that events have followed other than a clear and orderly sequence.
That, I say, is the natural and obvious teaching of the circumstantial evidence contained in the stratified rocks. I leave you to consider how far, by any ingenuity of interpretation, by any stretching of the meaning of language, it can be brought into harmony with the Miltonic hypothesis.
There remains the third hypothesis, that of which I have spoken as the hypothesis of evolution; and I purpose that, in lectures to come, we should discuss it as carefully as we have considered the other two hypotheses. I need not say that it is quite hopeless to look for testimonial evidence of evolution. The very nature of the case precludes the possibility of such evidence, for the human race can no more be expected to testify to its own origin, than a child can be tendered as a witness of its own birth. Our sole inquiry is, what foundation circumstantial evidence lends to the hypothesis, or whether it lends none, or whether it controverts the hypothesis. I shall deal with the matter entirely as a question of history. I shall not indulge in the discussion of any speculative probabilities. I shall not attempt to show that Nature is unintelligible unless we adopt some such hypothesis. For anything I know about the matter, it may be the way of Nature to be unintelligible; she is often puzzling, and I have no reason to suppose that she is bound to fit herself to our notions.
I shall place before you three kinds of evidence entirely based upon what is known of the forms of animal life which are contained in the series of stratified rocks. I shall endeavor to show you that there is one kind of evidence which is neutral, which neither helps evolution nor is inconsistent with it. I shall then bring forward a second kind of evidence which indicates a strong probability in favor of evolution, but does not prove it; and, lastly, I shall adduce a third kind of evidence which, being as complete as any evidence which we can hope to obtain upon such a subject, and being wholly and strikingly in favor of evolution, may fairly be called demonstrative evidence of its occurrence.
THE TRANSMISSION OF YELLOW FEVER BY MOSQUITOES
GEORGE M. STERNBERG, M.D., L.L.D, SURGEON-GENERAL U.S. ARMY[72][!--Note--]
This article is a scientific demonstration of a new fact. It shows clearly the processes of scientific reasoning based on the methods known to Logic as the Methods of Agreement and Difference. The theory that the germs of the disease are carried by mosquitoes seems first to have suggested itself to Dr. Sternberg and to Dr. Finlay through noticing a similarity of phenomena in many cases under different conditions. Yet, however plausible, the theory, neither of them could declare that he had discovered the fact until the experiments carried on under rigorous precautions had been tried. By these experiments all other causes were ruled out of consideration.
The discoveries which have been made in the past twenty-five years with reference to the etiology[73][!--Note--] of infectious diseases constitute the greatest achievement of scientific medicine and afford a substantial basis for the application of intelligent measures of prophylaxis.[74][!--Note--] We know the specific cause ("germ") of typhoid fever, of pulmonary consumption, of cholera, of diphtheria, of erysipelas, of croupous pneumonia, of the malarial fevers, and of various other infectious diseases of man and of the domestic animals, but, up to the present time, all efforts to discover the germ of yellow fever have been without success. The present writer, as a member of the Havana Yellow Fever Commission, in 1879, made the first systematic attempt to solve the unsettled questions relating to yellow fever etiology by modern methods of research.
Naturally the first and most important question to engage my attention was that relating to the specific infectious agent, or "germ," which there was every reason to believe must be found in the bodies of infected individuals. Was this germ present in the blood, as in the case of relapsing fever; or was it to be found in the organs and tissues which upon post-mortem examination give evidence of pathological changes, as in typhoid fever, pneumonia, and diphtheria; or was it to be found in the alimentary canal, as in cholera and dysentery? The clinical history of the disease indicated a general blood infection. As my equipment included the best microscopical apparatus made, I had strong hopes that in properly stained preparations of blood taken from the circulation of yellow fever patients my Zeiss 1-18 oil immersion objective would reveal to me the germ I was in search of. But I was doomed to disappointment. Repeated examinations of blood from patients in every stage of the disease failed to demonstrate the presence of microorganisms of any kind. My subsequent investigations in Havana, Vera Cruz, and Rio de Janeiro, made in 1887, 1888, and 1889, were equally unsuccessful. And numerous competent microscopists of various nations have since searched in vain for this elusive germ. Another method of attacking this problem consists in introducing blood from yellow fever patients or recent cadavers into various "culture media" for the purpose of cultivating any germ that might be present. Extended researches of this kind also gave a negative result, which in my final report I stated as follows: