[248] Duclaux, E., Traité de microbiol., 1898, i., 280.

[249] A full discussion of the literature on temperature coefficients is given in A. Kanitz’s book on Temperatur and Lebensvorgänge, Berlin, 1915.

[250] Van Slyke, D. D., and Cullen, G. E., Jour. Biol. Chem., 1914, xix., 141.

[251] These considera­tions may meet the objec­tions of Krogh to the applica­tion of the van’t Hoff rule of temperature effect on reac­tion velocity to life phenomena. See also the discussion of this subject in Kanitz’s book.

[252] Lillie, F. R., and Knowlton, E. P., Zoöl. Bull., 1897, i.

[253] Hertwig, O., Arch. mikrosk. Anat., 1898, li., 319. See also E. Cohen, Vorträge für Aerste über physikalische Chemie. 2d ed. Leipzig, 1907.

[254] Loeb, J., Arch. f. d. ges. Physiol., 1908, cxxiv., 411; Loeb J., and Wasteneys, H., Biochem. Ztschr., 1911, xxxvi., 345; Loeb J., and Chamberlain, M. M., Jour. Exper. Zoöl., 1915, xix., 559.

[255] Loc. cit.

[256] Kanitz, A., loc. cit., p. 123.

[257] Loeb, J., and Chamberlain, M. M., Jour. Exper. Zoöl., 1915, xix., 559.