Scarcely had they taken their seats at the table, when the two victims successively fell down insensible, from the virulence of the poison, and were carried to bed. The Pontiff rallied so far as to recover consciousness, and to linger for about a week, but at length sank under the shock and the fever which supervened, his age being seventy-one, and his constitution enervated by long debauchery. The last sacraments were duly administered, and it was remarked that, during his illness, he never alluded to his children Cesare and Lucrezia, through life the objects of an overweening, if not criminal fondness, in whose behalf most of his outrages upon the peace and the rights of mankind had been committed. His death occurred on the 18th of August.[*8]
Such is the account of this awful retribution given by Tommasi, from which most other narratives but slightly deviate as to dates or immaterial details. Another version, however, occurs in Sanuto's Diaries, which, being contemporary, and probably supplied from the diplomatic correspondence of the Signory, merits notice, and has not been hitherto published. The Cardinal of Corneto, who figures prominently in this narrative, was made collector for Peter's pence in England, and Bishop of Hereford, from whence he was translated to Bath and Wells. We shall find him compromised in Petrucci's conspiracy against Leo X., but the following charge of pope-poisoning is new.
"The Lord Adrian Castillense of Corneto, Cardinal Datary, having been desired by the Pope to receive him and Duke Valentino at supper in his vineyard, his Holiness supplying the eatables, this Cardinal presumed the invitation to be planned for his death by poison, so that the Duke might obtain his money and benefices, which were considerable. In order to save himself there seemed but one course, so, watching his opportunity, he summoned the Pontiff's steward, whom he knew intimately, and on his arrival received him alone in a private chamber, where 10,000 ducats were laid out: these he desired him to accept for love of him, offering him also more of his property, which he declared he could continue to enjoy only through his assistance, and adding, 'You certainly are aware of the Pope's disposition, and I know that he and the Duke have designed my death by poison through you; wherefore I pray you have pity on me and spare my life.' The steward, moved with compassion on hearing this, at length avowed the plan concerted for administering the poison; that, after the supper, he was to serve three boxes of confections, one for the Pope, another for the Duke, and a third for the Cardinal, the last being poisoned; so they arranged that the service of the table should be contrived in such a way that the Pontiff might eat of the Cardinal's poisoned box, and die. On the appointed day, the Pope having arrived at the vineyard with the Duke, the Cardinal threw himself at his Holiness' feet and kissed them, saying he had a boon to request, and would not rise until it were granted. The Pope assuring him of his consent, he continued, 'Holy Father! on the lord's coming to his servant's house, it is not meet that the servant should sit with his lord; and the just and proper favour I ask is permission for the servant to wait at the table of your Holiness.' The supper being thus served, and the moment arrived for giving the confections, the box having been poisoned by the steward as directed by the Pope, the Cardinal placed it before his Holiness, who, relying on his steward, and convinced of the Cardinal's sincerity by his service, ate joyfully of this box, as did the Cardinal of the other, which the Pontiff believed the poisoned one. Thereafter, at the hour when from its nature the poison took effect, his Holiness began to feel it, and thus he died: the Cardinal being still alarmed, took medicine and an emetic, and was easily cured."
The death of Alexander by poison is generally credited, although Raynaldus and Muratori, willing to mitigate so heinous a scandal, incline to the few and obscure authorities who attribute it to tertian fever. It was natural that the truth should be glossed over, especially in despatches addressed to the court of his daughter Lucrezia, to which the latter annalist probably had access. But though the earliest intelligence of the event forwarded by the Venetian envoy alludes to the Pope's seizure as fever, his subsequent letters, quoted by Sanuto, thus loathsomely confirm the current suspicion of poison having been administered. "On this day [19th] I saw the Pontiff's corpse, whose apparel was not worth two ducats. He was swollen beyond the size of one of our large wine-skins. Never since the Christian era was a more horrible and terrible sight witnessed. The blood flowed from ears, mouth, and nose faster than it could be wiped away; his lips were larger than a man's fist, and in his open mouth the blood boiled as in a caldron on the fire, and kept incessantly flowing as from a spout; all which I report from observation."[9]
The character of Alexander VI. as a man and as a sovereign admits of no question, and is thus forcibly summed up by Sismondi. "He was the most notoriously immoral man in Christendom; one whose debauchery no shame restrained, whose treaties no good faith sanctioned, whose policy was never guarded by justice, to whose vengeance pity was unknown."[*10] As a pontiff he must be tried by a different test, and those ecclesiastical writers, who attempt not to defend his morals or example, assert the orthodoxy of his faith and doctrine, and commend the wisdom of his provisions for maintenance of that religion which regarded him as its head. He was the first to establish the censorship of books,[*11] an important bulwark of the Roman Church; and among the orders which he instituted or protected was that of S. Francesco di Paolo. Nor can it be doubted that his ambitious nepotism eventually aggrandised the temporal possessions of the papacy, by quelling the mutinous barons of the Campagna, and by so crushing the more distant seigneurs as to render their states a speedy and easy prey to Julius II. On the other hand, the openly simoniacal practices which prevailed during his reign, the strong measures adopted to raise money for his private ends by a lavish scale of indulgences, and, generally, the unscrupulous employment of the power of the keys and the treasures of the Church for unworthy purposes, all tended to alienate men's minds, and to stir those doubts which the different, but not less injudicious, policy of his immediate successors ripened into schism.
Favoured by youth, constitution, and energy of mind, Cesare Borgia wrestled successfully with the deadly ingredients which he had inadvertently swallowed. He is said to have been saved by being frequently placed in the carcass of a newly-killed bullock or mule, and, whether in consequence of this treatment, or of the inflammatory nature of the potion, to have lost the whole skin of his body. He had flattered himself that, foreseeing every possible contingency which his father's death could develop, he had so planned his measures as to secure, in any event, his own safety, and the maintenance of his authority. But, never having anticipated being disabled from action at that very juncture, his well-laid schemes fell to the ground, a signal illustration of the proverb, "Man proposes, God disposes." By means of Don Michelotto, he was, however, able to draw round the Vatican a body of twelve thousand devoted troops, and that unscrupulous agent executed his instructions by seizing about 500,000 ducats in money, jewels, and valuables, from the Pope's apartment, before his death was published.
The Diaries of Sanuto give a lively description of the immediate effects of Alexander's death on Lower Italy,—the exultations of the people, the prompt movements of the Campagna barons, the hesitation of Valentino, the intrigues of the cardinals. As soon as the good news transpired, Rome rose in arms against the Spaniards; and the Colonna and the Orsini, entering at the head of their troops, willingly aided in spoiling and slaughtering these countrymen of the Borgia, who "could nowhere find holes to hide in." Even their cardinals narrowly escaped a general massacre; and on the 8th of September, a proclamation by the College cleared the city of these foreigners on pain of the gibbet. Duke Valentino, although prostrated in strength, and "seeming as if burnt from the middle downwards," was not without formidable resources. His hope was, that in the distracted state of Rome, the cardinals would provide for their personal safety by holding the conclave in St. Angelo, where the election would be in his own hands. This calculation was, however, defeated by their assembling at the Minerva convent, guarded by the barons of Bracciano and Palestrina, with the bravest of the citizens, and protected by barricades which withstood an assault by the redoubted Michelotto. Still his troops were staunch, the Vatican and St. Angelo were his, and he had secured the treasure of the Holy See. But his nerve gave way, and after turning the castle guns against the Orsini palace on Monte Giordano, he fled in a litter to the French camp without the gates, on the 1st of September, and thence made his way to the stronghold of Nepi. This vacillation brought its fitting recompense, and lost him the advantages of his position. Hesitating betwixt the Colonna and Orsini factions, wavering between Spanish and French interests, his friends dropped off, his forces melted away, and he lost the favourable moment for swaying the papal election.
The rival parties in the conclave, having had no time to mature their plans, in consequence of the late Pontiff's sudden decease, trusted to strengthen their respective interests by delay, and so were unanimous in choosing, on the 22nd of September, the most feeble of their body, the respected Piccolomini, who survived his exaltation as Pius III. but twenty-six days. The state of matters at Naples added to the general embarrassment. The ceaseless struggles for that crown had of late taken a new turn, the contest being now between Louis of France and Ferdinand of Spain. The Borgia, long adherents of the former, had recently inclined to the Spanish side; but their influence was now irretrievably gone.
*Note.—The following is a list of the chief conquests of Cesare:—
| City. | Family. | Date. | Campaign. |
| Imola | Riarii | Nov. 27, 1499 | First. |
| Forlì | Riarii | Jan. 12, 1500 | First. |
| Rimini | Malatesta | Oct. 10, 1500 | Second. |
| Pesaro | Sforza | Oct. 21, 1500 | Second. |
| Faenza | Manfredi | April 25, 1501 | Second. |
| Piombino | Appiani | Sept. 3, 1501 | Second. |
| Urbino | Montefeltri | June 21, 1502 | Third. |
| Camerino | Varani | July 29, 1502 | Third. |
| Sinigaglia | Roveri | Dec. 28, 1502 | Third. |
| Città di Castello | Vitelli | Jan. 2, 1503 | Third. |
| Perugia | Baglioni | Jan. 6, 1503 | Third. |
| Siena | Petrucci | Jan. (end), 1503 | Third. |