Virginia, married in 1560 to Count Federigo Borromeo, whose premature death is said to have frustrated a project of his uncle, Pius IV., for investing him with Camerino. She afterwards married Ferdinando Orsini, Duke of Gravina, and, dying in childbed, left to her father about 180,000 scudi.
The children of his second marriage were,—
1. Francesco Maria, his heir.
2. Isabella, married in 1565 to Nicolò Bernardino di Sanseverino, Prince of Bisignano, a Neapolitan nobleman, with a fine fortune, but greatly encumbered. She was a princess of generous and attractive character, and died in 1619 without surviving issue.
3. Lavinia, said in the Venetian Relazione of Zane to have been betrothed to Giacomo Buoncompagno natural son of Gregory XIII., but the nuptials never took place. She afterwards married Alfonso Felice d'Avalos d'Aquino, Marquis of Guasto, son[*75] of the famous Vittoria Colonna, and died in 1632, aged seventy-four.
(From similarity of name, this princess has been confused with her second cousin Lavinia Franciotti della Rovere, wife of Paolo Orsini, whose intimacy with Olympia Morata is well known to those who trace the quickly smothered seeds of Protestantism in Italy.)
Guidobaldo left also two natural daughters,—
1. ——, married, first, to Count Antonio Landriano of Pesaro; secondly, to Signor Pier-Antonio da Lunà of Castella, in the Milanese.
2. ——, married to Signor Guidobaldo Renier.