The most important event in the history of the institution, after its foundation, was its establishment in the home which it was to occupy down to our own time. Its new habitation was prepared for it by the Pope who has probably been the most maligned in history--Alexander VI. A magnificent site was appropriated for it, and the construction of suitable buildings begun. A little more than a decade later, Leo X., another one of the misunderstood Popes, came to the conclusion that the two universities in Rome, that of the Papal Court and that of [{232}] the City, would do better work if combined into one, and accordingly this combination was effected. This made provision for one very strong teaching faculty in Rome. The final steps for the completion of the union of the two universities were taken by Pope Alexander VII., and the buildings which the new university was to occupy were finished in a manner worthy of the great institution of learning which it was hoped to create in Rome.
The first of the great professors who made the Papal Medical School famous was Realdo Colombo, often spoken of as Columbus simply, who was invited to teach in Rome by Pope Paul III., the same Pope who issued the bull founding the Jesuits. Some people might consider the two actions as representing contrary tendencies in education, but they are not such as know either the history of the Jesuits, or of the constant endeavor of the Popes to foster education. Columbus came to Rome, as we have said, with the prestige of having succeeded Vesalius at Padua, and later having been specially tempted by the reigning prince in Pisa, who wanted to create a great medical school in connection with his university in that city, which he was at that moment trying to raise to distinction, to accept the professorship of anatomy there.
Vesalius was still alive at this time, and the period when, if we would credit certain historians who emphasize the opposition between the Church and science, it was dangerous to dissect human bodies had not yet passed. It is interesting to read the account of Columbus's reception in Rome, and the interest manifested in his work by all classes in the Roman University at this time. His course in anatomy was so enthusiastically [{233}] attended that, as he himself tells in a letter to a friend, he often had several hundred persons in his audience when he gave his anatomical demonstrations on the cadaver. These were not all medical students, but many of them were ecclesiastics, and some of them important members of the hierarchy. Even cardinals manifested their interest in anatomy, and occasionally attended the public dissections--public, that is, as far as the University is concerned--which were made by Columbus.
Columbus's enthusiasm for anatomy was such that, as Dr. Fisher said of him in the Annals of Anatomy and Surgery, Brooklyn, 1878-1880, "he dissected an extraordinary number of human bodies, and so devoted himself to the solution of problems in anatomy and physiology that he has been most aptly styled the Claude Bernard of the sixteenth century." In one year, for instance, he is said to have dissected no less than fourteen bodies, demonstrating, as Dr. Fisher has said, that "it was an age of remarkable tolerance for scientific investigation."
Besides being an investigator, Columbus was a great teacher, and many of our modern methods of instruction in medical schools had their origin in the system of demonstrations introduced by him. His descriptions of the demonstrations for students upon living animals, show that some of the most recent ideas in medical teaching were anticipated by this Roman professor of anatomy and medicine in the Renaissance period. His demonstrations of the heart and blood-vessels and of the actions of the lungs are particularly complete, and must have given his students a very practical working knowledge of these important physiological functions. In a word, the medical teaching of the Roman [{234}] University, under him at this time, far from being merely theoretic and distant from actual experience and demonstration, was thoroughly modern in its methods.
It is no wonder, then, that practically all the ecclesiastical visitors who came in such numbers to Rome, made it a custom at this time to attend one or more of Columbus's anatomical lectures. They were looked upon as one of the features of the Roman university life of the time. How much good was accomplished by this can scarcely be estimated. The example must have had great influence especially on members of faculties of various educational institutions who came to the Papal See. To some degree at least these interesting teaching methods must have aroused in such men the desire to see them emulated in their own teaching institutions, and therefore must have done much to advance medical education. The fact that these things were done in the Papal Medical School only emphasized the significance of them for ecclesiastics, and made them more ready to bring about their imitation in other teaching centers.
How well the Popes were justified in their estimation of Columbus's genius as an anatomical investigator will be best appreciated from his discovery of the pulmonary circulation, which formed, as Harvey confesses at the beginning of his work on the circulation, the foundation on which Harvey's great discovery naturally arose. It is probable that Columbus would not have come to Rome, in spite of the flattering offers held out to him, only that he was already the personal friend of a number of high ecclesiastics, and even of the Pope who extended the invitation. How well the Popes continued to think of Columbus after his years of work in the [{235}] Roman Medical School will be well understood from the fact that, when his great work De Re Anatomica was published after his death by his sons, Pope Pius IV. accepted the dedication of it. This was of course not an unusual thing, for many books on other sciences were dedicated to the Popes, and the example thus set was subsequently imitated. Twenty-five years later, Professor Piccolomini dedicated his Anatomical Lectures to Pope Sixtus V. Subsequent anatomical publications of the Papal Medical School were issued under like patronage. The famous edition of Eustachius's anatomical sketches, published under the editorship of Lancisi, is a notable example of this, and went to press mainly at the expense of Pope Clement XI., who realized how valuable they were likely to be for the teaching of anatomy.
These two great discoverers in anatomy, Columbus and Eustachius, were succeeded, as is so often the case in the history of university faculties, by a man more capable of writing about great discoveries than of making them himself. This was Piccolomini, who devoted himself to showing how much the ancients had taught about anatomy, though at the same time he also made clear the place occupied by modern anatomical discoveries. While his name is not attached to any great discovery in the science of anatomy, he is generally acknowledged to have been one of the great teachers of his time and one who was needed just then in order to make people realize how the old and the new in anatomy must be coordinated. Piccolomini's successor in the chair of anatomy at Rome was another original genius and investigator whose name, however, and fame has never been as great among English-speaking people as in Italy, or among the Latin races generally. The fact that he was a rival [{236}] of Harvey's in the matter of the discovery of the circulation of the blood has always made the Italians exaggerate his position in medical history, while it has undoubtedly made English writers of medical history diminish the importance of his work.
Historians of science consider him worthy to be called the greatest living scientist of his time--the end of the sixteenth century. He was not only a scientific physician, but he was an authority in all the sciences related to medicine, and indeed had profound interests in every branch of physical science. His contemporaries looked up to him as a leader in scientific thought. To anyone who examines the question of the discovery of the circulation of the blood with freedom from bias, there can be no doubt but that the honor for this discovery has been unduly taken away from Caesalpinus in English-speaking countries, to be conferred solely on Harvey. Not that there is any wish to lessen the value of Harvey's magnificent original work, nor make little of his wonderful powers of observation, nor of the marvelous experimental and logical method by which he followed out his thoughts to their legitimate conclusion, but that I would insist on giving honor where honor is due, though most writers in English refuse to give Caesalpinus's claims a proper share of attention.
The Italians have always declared that Caesalpinus was the real discoverer of the circulation, and there is no doubt that his career occurs just at that point in the evolution of the medical sciences, and especially anatomy and physiology in Italy, where this discovery would naturally come. Lest it should be thought, however, that my interest in the Popes and the Papal Medical School has led me to exaggerate the claims of [{237}] Caesalpinus as a great naturalist and medical scientist, I prefer to quote the description of him given by Professor Michael Foster in his lectures on the History of Physiology, delivered in this country as the Lane Lectures, at the Cooper Medical College in San Francisco, and published by the Cambridge University Press, 1901. Professor Foster was not one to exaggerate the claims of any Italian, and least of all of any Italian who might be supposed to have a claim that would stand against Harvey's. The soupçon of Chauvinism in his treatment of Servetus and Columbus in this regard is indeed rather amusing. He said:--