Typhoid fever13.86
Measles9.01
Scarlet fever4.87
Whooping cough10.11
Diphtheria and croup16.30
Tuberculosis (all forms)144.52
Cancer and other malignant tumors80.27
Cerebral hemorrhage, apoplexy78.91
Acute endocarditis and organic diseases of the heart153.65
Pneumonia (all forms)152.98
Acute nephritis and Bright's disease101.63

The death rate from diseases of the nervous system is of particular interest. The average annual rate per 100,000 of the population for the years 1916, 1917, 1918 and 1919 was as follows:

Encephalitis1.0
Meningitis (total)8.17
Locomotor ataxia2.27
Other diseases of the spinal cord (total)8.57
Cerebral hemorrhage, apoplexy80.57
Softening of the brain1.25
Paralysis without specified cause7.65
General paralysis of the insane6.77
Other forms of mental alienation2.17
Epilepsy4.07
Chorea.10
Other diseases of the nervous system3.85

This shows a total death rate for nervous and mental diseases of 126.44 per 100,000. It is a fairly reasonable assumption that of the above, the following, at least, may be classified as having been definitely associated with psychoses:

Rate per 100,000
Encephalitis1.0
Meningitis8.17
Softening of the brain1.25
General paralysis of the insane6.77
Other forms of mental alienation2.17

We may, therefore, reasonably conclude that there was an average number of at least 19.36 per 100,000 (from 1906 to 1910 this amounted to 32.1) in which the primary cause of death was associated with mental diseases, an exceedingly conservative estimate. This does not take into consideration the deaths due to senility (15.5) or suicide (12.8), conditions which might very logically be included for obvious reasons. It is, of course, well known that the psychoses rarely, if ever, appear in the death certificates as a primary cause of death. As a matter of fact, they are not always shown in the secondary causes. Information on this subject is still less satisfactory from a statistical point of view. During the year 1917 (contributory causes have not been reported since that year) there was a total of 1,066,711 primary causes of death shown in the registration area and only 372,291 contributory causes. Of this number the following may be classified as having been associated with psychoses:

DiseasePrimary
Cause
Contributory
Cause
Encephalitis620904
Meningitis (total)6,6736,815
Softening of the brain888722
General paralysis of the insane5,248648
Other forms of mental alienation1,6513,895
——————
Total15,08012,987

The contributory causes definitely showing mental diseases constitute only 3.4 per cent of the whole number, and the death rate for 1917, including both primary and contributory causes suggestive of probable psychoses, was 37.2 per 100,000. This would indicate that the number of deaths from mental diseases shown in the primary causes represents only about fifty-three per cent of all mental cases which are actual factors in determining the death rate of the community. A comparison of these figures with the number of cases dying in hospitals shows that they cannot be looked upon as determining the percentage of the general population showing psychoses. Of the 1,952 persons dying in the institutions for mental diseases in Massachusetts in 1919, approximately nineteen per cent showed the psychoses in the primary causes of death. This percentage would probably be fairly constant throughout the country. It is, of course, a well recognized fact that the death certificate at best is not beyond suspicion and does not furnish information regarding the cause of death which can be accepted without question.

Dr. Richard C. Cabot[1] has made an elaborate study of errors in diagnosis as shown by autopsies. His work shows the following percentage of diagnostic accuracy:

Per cent.
Diabetes mellitus95
Typhoid fever92
Aortic regurgitation84
Lobar pneumonia74
Cerebral tumor72.8
Tubercular meningitis72
Gastric cancer72
Mitral stenosis69
Brain hemorrhage67
Aortic stenosis61
Phthisis, active59
Miliary tuberculosis52
Chronic interstitial nephritis50
Hepatic cirrhosis39
Acute endocarditis39
Bronchopneumonia33
Acute nephritis16