No person can be too careful in the use of laudanum, paregoric, and morphine. They may be taken on a physician's prescription as a sedative from racking pain, [Footnote: Many persons learn to inject morphine beneath the skin by means of a "hypodermic syringe." The operation is painless, and seems an innocent one. It throws the narcotic directly into the circulation, and relief from pain is often almost instantaneous. But the danger of forming the opium habit is not lessened, and the effect of using the drug in this form for a long time is just as injurious as opium smoking itself. Opium in one of its forms enters largely into the composition of many of the painkillers and patent medicines so freely advertised for domestic use in the present day, and for this reason the greatest care is needed in having recourse to any of them. Taken, perhaps, in the first instance, to alleviate the torments of neuralgia or toothache, what proves to be a remedy soon becomes a source of gratification, which the wretchedness that follows on abstinence renders increasingly difficult to lay aside. The same must be said of bromide of potassium and hydrate of chloral, frequently resorted to as a remedy for sleeplessness: the system quickly becomes habituated to their use, and they can then be relinquished only at the cost of much suffering. Indeed, the last mentioned of these two drugs obtains over the mind a power which may be compared to that of opium, and is, moreover, liable to occasion the disease known as chloralism, by which the system ultimately becomes a complete wreck. Looking at the whole question of the medicinal use of narcotics, it is perhaps not too much to say that they should never be employed except with the authority of a competent medical adviser.— Chambers's Journal.] but if followed up for any length of time, the powerful habit may be formed ere one is aware. Then comes the opium eater's grave, or the opium eater's struggle for life!

4. CHLORAL HYDRATE.

CHLORAL HYDRATE is a drug frequently used to cause sleep. It leaves behind no headache or lassitude, as is often the case with morphine. It is, however, a treacherous remedy. It is cumulative in its effects, i. e., even a small and harmless dose, persisted in for a long period, may produce a gradual accumulation of evil results that in the end will prove fatal.

THE PHYSIOLOGICAL EFFECT of its prolonged use is very marked. The appetite becomes capricious. The secretions are unnatural. Nausea and flatulency often ensue. Then the nervous system is involved. The heart is affected. Sleep, instead of responding to the drug, as at first, is broken and disturbed. The eyesight fails. The circulation is enfeebled, and the pulse becomes weak, rapid, and irregular. There is a tendency to fainting and to difficult respiration. Sometimes the impoverished blood induces a disease resembling scurvy, the ends of the fingers ulcerate, and the face is disfigured by blotches. An excessive dose may result in death.

Prolonged habitual use of chloral hydrate tends to debase the mind and morals of the subject in the same manner as indulgence in alcohol, ether, or chloroform.

5. CHLOROFORM.

CHLOROFORM is an artificial product generally obtained, by distillation, from a mixture of chloride of lime, water, and alcohol. It was discovered in 1831 by Samuel Guthrie, of Sackett's Harbor, New York. It is a colorless, transparent volatile liquid, with a strong ethereal odor.

PHYSIOLOGICAL EFFECT.—Chloroform is a powerful anæsthetic, which, when inhaled, causes a temporary paralysis of the nervous system, and thus a complete insensibility to pain. There is great peril attending its use, even in the hands of the most skillful and experienced practitioners. It is sometimes prescribed by a physician, and afterward (as in the case of laudanum, morphine, and chloral) the sufferer, charmed with the release from pain and the peaceful slumber secured, buys the Lethean liquid for himself. Its use soon becomes an apparent necessity. The craving for the narcotic at a stated time is almost irresistible. The patient, compelled to give up the use of chloroform, will demand, entreat, pray for another dose, in a heartrending manner, never to be forgotten. Paleness and debility, the earliest symptoms, are followed by mental prostration. Familiarity with this dangerous drug begets carelessness, and its victims are frequently found dead in their beds, with the handkerchief from which they inhaled the volatile poison clutched in their lifeless hands.

6. COCAINE.

Cocaine is an alkaloid prepared from the erythroxylon coca, a shrub, five or six feet high, found wild in the mountainous regions of Ecuador and Peru, where it is also cultivated by the natives. The South American Indians, for centuries, have chewed coca leaves as a stimulant, but the highly poisonous principle, now called cocaine, to which the plant owes its peculiar effects, was not discovered till 1859. Within a few years this drug has come into favor as an agent to produce local anæsthesia, and has proved exceedingly valuable in surgical operations upon the eye and other sensitive organs. It has already, however, been diverted from its legitimate use as a benefaction, and to the other evils of the day is now added the "cocaine habit," which is, perhaps, even more dangerous and difficult to abandon than either the alcohol or the opium habit.