"At the same time [that] the pulse of the artery is perceived by touch, the vena cava is attracted, as it were."[239]
We will not now search for what he meant by saying that "the vena cava is attracted, as it were." Clearly, however, in denying that it pulsates, he meant not to deny that its wall moves rhythmically, but to deny only that this movement is of the nature of what he styles pulsation in the case of the auricles or the ventricles, or the arteries, or the arterial vein.
We know not what influence the rhythmic movements of the wall of the vena cava may have had upon Harvey's transfer to its cavity of the Aristotelian seething of the blood. To this was referable the palpitation seen by him in the blood itself as the first sign of life in the embryo and the last sign of life in the dying animal; and in this same familiar seething he found ready to his hand a life-long cause for the visible sharp expansion of the auricle in its diastole, for which expansion he could find no such obvious muscular cause as for the corresponding expansion of the ventricle or the arteries. The seething of the blood, however, was carefully kept by him below the point of vaporization and adapted to maintain the circulation by keeping the muscular cardiac pump at work.
Connected with Harvey's doctrine of the cause of the heart-beat there is a point which a student of his thought may find knotty, despite the aid of a well-developed historical sense. Harvey made the systolic contraction of auricle or ventricle dependent on the mechanical stimulus of its next preceding diastolic distension. It is not quite easy to see how he found this process compatible with the orderly recurrence of all the systolic contractions in the beating of a nearly empty heart. It is well known that the heart may beat for a while when cut out of the body, when, therefore, the heart is nearly drained of blood. In the treatise of 1628 Harvey himself speaks of studying the ventricular systole of "the heart of an eel, taken out and laid upon the table or the hand"; and says that the phenomena seen in this are seen likewise "in the hearts of little fishes, and in those colder animals in which the heart is conical or elongated."[240] In his lecture notes he says, we remember, that "the auricles pulsate after removal of the heart, because of the multitudinous blood."[241] But this jotting, written only as a brief reminder for himself, is obscure to others. By the word "heart" Harvey means sometimes the ventricular mass without the auricles and sometimes the ventricular mass and the auricles taken together. Hence it is uncertain whether the above reference be to auricles left attached to the body or removed with the ventricular mass. In neither case is it easy to imagine effective distention produced by the seething even of "the multitudinous blood." However, in the same lecture notes a few pages farther on Harvey says: "Nevertheless, the heart pulsates, cut away from the auricles;"[242] and in the treatise of 1628 he says:—
"The heart of the eel and of some fishes, and of animals even, when taken out, pulsates without auricles; indeed, if you cut it in pieces you shall see its divided parts contracting and relaxing separately; so that in these creatures the body of the heart pulsates and palpitates after the auricles have ceased to move. Is this, however, peculiar to the animals which are more tenacious of life, whose radical moisture is more glutinous, or rich, and sticky,[243] and not so readily dissolved? For in eels the thing is apparent even in their flesh, which retains the power of motion after they have been skinned, drawn, and cut in pieces."[244]
At this point we may recall the following words of our author:—
"I affirm also that in this way the native heat or innate warmth, being the common instrument of all the functions, is likewise the prime efficient cause of the pulse."[245]
Should we hazard the improbable guess that Harvey meant his cause of the heart-beat to be effective only in warm-blooded animals, we must remind ourselves that it certainly was well known to him as to all the other physicians of his day that the heart of the mammal beats after excision. If few had made experiments, all had studied Galen; and Galen cites the beating of the heart after excision as evidence that its beat does not depend upon the nervous system, the context making it obvious that he refers to the heart-beat of the mammal. Moreover, he makes it evident that the striking phenomenon in question must have been seen by the ancients at the altar, as an incident of sacrificial rites.[246] This fact makes it easy to understand how it happened that earlier still, at least two centuries before Galen's time, the layman Cicero, one of Harvey's favorite authors, should have made a stoic say:—