In the earlier epidemics, of which we read, one of the most remarkable circumstances, was the extraordinary influence the poisonous matter appeared to

exercise over the lungs,[[64]] and they again, were the means of propagating the disease, and spreading the contagious particles through the atmosphere, for we read: "Thus did the plague rage in Avignon for six or eight weeks, and the pestilential breath of the sick, who expectorated blood, caused a terrible contagion far and near, for even the vicinity of those who had fallen ill of plague was certain death; so that parents abandoned their infected children, and all the ties of kindred were dissolved."[[65]] "The like was seen in Egypt. Here also inflammation of the lungs was predominant." "Here too the breath of the sick spread a deadly contagion."

It is more than probable that all infectious matter obtains an entrance to the system through the lungs. Inspiring the air containing the pestilential semina is, indeed, the only plausible explanation of infection; for though the skin is indubitably an absorbing

surface, and capable of taking up and conveying to the blood any noxious matter applied to it, yet it is far more probable that the lungs would effect this process with greater rapidity. Then the stomach, the only other absorbing surface to which extraneous matter can be applied, is not likely to be the part where the elements of disease would obtain an entrance to the system, for many facts prove, that infectious matter may be swallowed without any injurious consequences, unless in a very concentrated state. Instances are not easily found of diseased matter having been swallowed, except where diseased vegetables have formed under some combination of circumstances, a portion of diet.[[66]]

Many facts are on record which prove the powerful effect of diseased grain when made into bread, and taken for any length time as a principal article of food. The history of Ergot of Rye is too fresh in the memory of most people to require more than an allusion here. The stomach had no power over the secale, its poisonous properties were retained, after having been submitted to the digestive process, as was evidenced by the abortions and gangrenes it occasioned.

But diseased wheat is also capable of inducing

gangrene, and it is more than probable, that many diseases might be traced to the use of infected grain of various kinds. An interesting account of a family who lived at Wattisham, near Stowmarket, in Suffolk, and all of whom suffered more or less from living on bread made of smutty wheat, may be found in the Philosophical Transactions. The mother of this family and five of the children, consisting of three girls and two boys, all suffered from gangrene of the extremities; the father lost the nails from his hands, and had ulceration of two of his fingers.[[67]] Dr. Woollaston wrote thus in a letter on this case: "The corn with which they made their bread was certainly very bad: it was wheat that had been cut in a rainy season, and had lain on the ground till many of the grains were black and totally decayed, but many other poor families in the same village made use of the same corn without receiving any injury from it. One man lost the use of his arm for some time, and still imagines himself that he was afflicted with the same disorder as Downing's family." It is not unlikely this was the case, for numbness and loss of power was one of the well marked characters of the disease.

What other afflictions may be due to diseased vegetation and adulterated articles of food, and what loss of life may accrue from cheap and adulterated

drugs and chemicals is hardly yet dreamt of.[[68]] The systematic practice of adulteration of almost every article of diet which comes to table has become a serious question for the legislature to consider. Take only the article of milk, upon which the young children of large towns and cities, make their chief meals, with the addition of bread. How much milk comes into London from the country, how much is obtained from stall and grain-fed cows in the metropolis, and how much is said to be consumed, would be an interesting calculation. It is pretty well known that a mixture is sold by which a retailer of milk may increase his supply by one-third or one-half. It was discovered in Paris that the brains of animals, when prepared in a particular manner, formed, when mixed with a certain proportion of milk and water, a very fine and deceptive cream; in that city this system was carried on to a considerable extent. I could not help alluding to these facts while speaking of diseased grain, for who shall say to what extent a miller in a large way of business, may be able to "work in," as it is called, a considerable amount of smutty corn in the manufacture of flour? Now, as diseased grain is known

to induce abortion, it is impossible to tell how small a portion may in some cases produce the effect; we may therefore say with Thomas of Malmesbury, "There is no action of man in this life which is not the beginning of so long a chain of consequences, as that no human providence is high enough to give us a prospect to the end."[[69]]