There is, in many instances, a strong analogy not only between antimony and orpiment, but the more virulent poison of white arsenic; and those who have been bold enough to use that poisonous mineral as a medicine, have found, in its preparations, a more certain and efficacious remedy than in those of antimony. The illustrious Stahl gives some account of a famous fever powder, which obtained great reputation in Germany, and was used by most of the nobility in his neighbourhood. This celebrated chymist does not deny its great efficacy, but, alarmed by a suspicion of poison in its composition, earnestly declaims against its use: it was at length acknowledged to be a preparation of white arsenic[42].
The same fever-powder, or a similar preparation, was used, with great success, by the German Physicians and Surgeons, in the late Flanders war. It was also introduced among the English, but the late Mr. Pringle, Inspector General of the British hospitals in Flanders, on whose authority this fact is related, alarmed at the danger and uncertainty of this remedy, ordered all the preparations of it to be destroyed. This gentleman acknowledged it had proved successful, but dropsies and visceral obstructions, which sometimes followed the fevers in which it was given, were, perhaps unjustly, ascribed to its use.
Some account of an arsenical fever-powder is given by Doctor Werlhoff, late physician to his Britannic Majesty at Hanover. He mentions its being recommended from successful experience by Michael Friccius[43], who had used some drachms of it, and by Sleuogtius[44], who had given it with safety in fifty cases, but, notwithstanding these and many other recommendations, he expressly condemns this dangerous remedy[45].
Lemery also affirms, that many diseases have been cured by giving four grains of white arsenic in a large quantity of water. It operates, according to this intelligent chymist, by vomiting, in the same manner as antimony. But he highly disapproves of using it as an internal remedy[46].
Poisons having been lately strongly recommended for the cure of many obstinate diseases, and generally adopted in practice, the dread of them, wisely implanted in our nature, is in a great measure banished; and such is the influence of novelty and fashion, and so much has prejudice prevailed, that one of the most eminent physicians in Europe has been disgraced for exposing a practice fraught with danger, and supported by misrepresentation[47].
But though the strong proofs of the poison of antimony, drawn from its natural history and chymical analysis, should be rejected by prejudice or scepticism, yet the easy transition of this mineral, by the simplest processes and slightest accidents, from a salutary medicine to a deadly poison, has not yet, been seriously denied.
It is found by chymists generally to contain mercury, arsenic, lead, sulphur, and sometimes copper, silver, and other metals[48]. When it is melted by fire, or deflagrated with half its weight of nitre, it becomes a poison. But if antimony, or its regulus, is mixed with an equal portion of common salt, and calcined with a gentle heat, stirring it constantly, and afterwards washing it with pure water, it becomes a gentle diaphoretic.
The mildest preparation of antimony; its white calx, which may be safely taken to the quantity of some drachms, if melted with an equal portion of nitre, a little powder of charcoal, and a small quantity of animal fat, is immediately rendered poisonous.