Continued inhalation of small quantities of sulphuretted hydrogen produces irritation of the mucous membrane, cough, and lacrymation; headache, giddiness, nausea, and mental dulness soon ensue; occasionally also symptoms of intestinal catarrh follow; if at this stage—or after a longer exposure to the action of a smaller amount—the patient is withdrawn from its further influence, there still continue for some time symptoms of irritation of the mucous membrane (such as inflammation of the conjunctiva and of the respiratory passages).

Further exposure or absorption of greater amounts induces general discomfort and passes on to a second stage of convulsions and delirium.

Inhalation of a large dose of sulphuretted hydrogen causes almost instantaneous death; the affected person falls dead—often without a sound—as if struck by a blow; occasionally a short stage of unconsciousness, with symptoms of suffocation, precede death.

This acute form often occurs, especially in acute sewer gas poisoning. Besides this, a sub-acute form of sewer gas poisoning is recognised which is attributable, in part at least, to the action of sulphuretted hydrogen, the prominent symptoms being irritation of the mucous membranes and of the intestinal canal. In other severe cases symptoms of the central nervous system preponderate (headache, giddiness, and delirium). These forms of poisoning can be caused not only by sulphuretted hydrogen, but also by other poisonous gases which are found in drains or sewers.

As regards treatment, continued inhalation of oxygen, supported by artificial respiration, is often, in serious cases, effective. In severe poisonings also saline injections and bleeding may be advocated. Other symptoms (catarrh, &c.) must be treated symptomatically.

CARBON BISULPHIDE

Pure carbon bisulphide (CS₂) is a colourless, peculiar-smelling liquid which boils at 46° C.

As Lehmann has shown, even 1·5 to 3·0 mg. CS₂ per litre of air produces distress—with acute symptoms of poisoning (congestion, giddiness, sickness, &c.).

Industrial carbon bisulphide poisoning is, however, chronic in nature and induced by continuous inhalation of small quantities of the fumes. To understand the action of carbon bisulphide, its capacity for dissolving fats and fatty substances must be taken into account. Its injurious effect extends to the nerve tissues (central and peripheral nervous system) and the glandular tissues.

Throughout chronic industrial carbon bisulphide poisoning, which has been described fully by Delpech, Laudenheimer, and others, nervous and psychical symptoms predominate, together with severe chronic digestive derangement.