Differential Count.

Lymphocytes9=2,450
Large mononuclears13=3,540
Polymorphonuclears78=21,220
Eosinophiles0=0
Mast cells0=0
100·0

The left knee joint was aspirated by Dr. Munro. A clear fluid of straw yellow tint was withdrawn, which yielded some fibrin on standing. The cytological examination gave the following results:—

Total Count.

44,800 per c. mm. (nearly all leucocytes).

Differential Count.

Polymorphonuclears92
Lymphocytes7
Large mononuclears1
Eosinophiles0
Basophiles0
100

Attempts at culture on broth and agar proved sterile. In addition three separate blood cultures, taken at intervals of a few days, on agar slopes and broth, all gave negative results.

In another instance of polyarticular distribution the subject was seen during the inter-paroxysmal period. He displayed auricular tophi, the crystalline content of which was verified microscopically.