So accurate and graphic were the clinical pictures of gout depicted by the ancient physicians that there is no doubt the gout of to-day conforms to the primitive type as met with among the Greeks and Romans. This certainly as regards the arthritic phenomena of the disease; for in those remote ages little or no account seems to have been taken of its irregular or ab-articular manifestations. While disregard of the latter group renders more credible their claims as to the widespread prevalence of the affection, nevertheless, I think there can be no doubt that the frequency of gout amongst the ancient Greeks and Romans was probably over-estimated.
Can it be questioned that a large percentage of the cases of gout in those bygone times consisted of undifferentiated infective forms of arthritis. Syphilis and gonorrhœa must have existed then as now, and their specific forms of arthritis, how easily confused with “rich man’s gout!” Surely too, they, like ourselves, must have suffered with states of oral sepsis, pyorrhœa alveolaris, etc., not to speak of infective disorders, with their correlated arthritides. In short, the differentiation of arthritic disorders was then hardly in its infancy, and it is in light of this disability that we must appraise their clearly extravagant assertions as to the widespread ravages of gout in their day.
But passing to more recent times, there is little doubt that the classical type of podagra is very much rarer to-day than, say, in the time of Sydenham. Indeed, it may be said to be becoming progressively infrequent. Thus, writing in 1890, Sir Dyce Duckworth tells us that some twenty-six years prior to that date, Sir George Burrows informed him that “he then saw fewer cases of acute gout than he was accustomed to see in his earlier practice.” It may be recalled, too, that Sir Charles Scudamore, in retrospect of his own experience, of still earlier date, was led to much the same conclusion. Moreover, not only is the disorder less frequent, but its virulence seems to have suffered attenuation, and this to a marked degree.
Again, Ewart, writing in 1896, observed that “goutiness” is becoming relatively more common than declared gout. This, he thought, by reason of the increasing attenuation in transmission of the “gouty” taint. In this, as well as the more mitigated character of the arthritic manifestations, he saw hope of “an ultimate extinction of the bias in ‘gouty’ families.” For, as he rightly says, side by side with “the tendency to a reproduction of morbid parental peculiarities, there is a yet stronger tendency in Nature to reproduce the healthy type of the race in each successive generation.”
But while there is a general consensus of opinion as to the growing rarity of acute regular gout, on the other hand, many, as if loth to part with the disorder, claim that pari passu with the decline of regular types the incidence of irregular manifestations grew proportionately.
In my experience the incidence of regular gout has appreciably diminished during the past twenty years. Moreover, such examples as one has met with incline much more in character to the asthenic than to the sthenic variety of podagra. But, in contrast to many, I have observed no increase in the irregular manifestations of gout. On the contrary, a steady diminution in the nebulous content of this category, but to this vexed subject we shall recur in a subsequent chapter dealing with the propriety or not of retaining this ill-defined term in medical nomenclature.
My conclusion, then, is that not only is arthritic gout becoming less prevalent, but that the type of the disease also has suffered attenuation. Probably this dual change is the outcome of many factors, not the least of these an increase in national sobriety. For as Sir Alfred Garrod long since observed, “There is no truth in medicine better established than the fact that the use of fermented liquors is the most powerful of all the predisposing causes of gout; nay, so powerful, that it may be a question whether gout would ever have been known to mankind had such beverages not being indulged in.
“Αυσιμελου Βάκχου, και λυσιμελους Αφοδίτης,
Γένναται θυχατηρ, λυσιμελὴς, Ποδὰγρα.”