Uric Acid Estimation in Normal Individuals

(McLester, “Archives of Internal Medicine.”)

Milligrams Uric Acid in 100 grams Blood.

J. C.0·5
H. D.0·6
M. D.0·6
A. B.0·8
R. C.0·9
H. D.0·9
J. G.0·0
S. M.1·1
R. D.1·3
L. S.1·4
L. H.1·7
R. O.2·1
H. H.2·5
J. M.2·5
R. E.2·9

Uric Acid of Blood in Disease. (McLester, “Archives of Internal Medicine.”)

Milligrams in 100 grams Blood.

Mitral lesion0·5
Rheumatic fever0·6
Acute syphilis0·8
Chronic tuberculous pleurisy0·8
Pneumonia1·2
Pneumonia1·3
Sciatica1·3
Typhoid fever1·4
Ulcer of stomach1·5
Pneumonia1·6
Amœbic dysentery1·6
Neurasthenia (?)1·7
Acute tuberculous pleurisy1·7
Chronic interstitial nephritis1·8
Malaria1·8
Pneumonia1·9
Uremia2·1
Polycythemia2·2
Graves’ disease2·5
Pneumonia2·7
Gout3·3
Arterial hypertension3·3
Intermittent gastric supersecretion3·7
Gout4·5

[22] However, as Walker Hall reminds us, Taylor, writing in 1912, stated, “That the margin of safety with regard to renal excretion is an exceedingly narrow one, that the kidney excretes uric acid slowly, and that its powers are soon overstepped.”

[23] Magnus Levy and McClure have also noted that the excretion of exogenous purin is not invariably retarded or diminished.

[24] When experimentally injected, the urates are absorbed slowly by phagocytic leucocytes and giant cells.—Gideon Wells.