| Normal. | |||||
|---|---|---|---|---|---|
| “R.A.”—Ratio of physiological acidity to excess of solids over water | 4·77 |
| |||
| “R.P.”—Ratio of total P₂O₄ to excess of solids over water | 11·17 | ||||
| “R.U.”—Ratio of urea to excess of solids over water | 100·53 | ||||
| “R.U.A.”—Ratio of uric acid to excess of solids over water | 2·33 | ||||
| “R.H.A.”—Ratio of hippuric acid to excess of solids over water | 7·3 | ||||
| “R.P./R.A.”—Ratio of phosphoric acid to ratio of acidity (Joulie’s factor, cf. Vol. I., p. 737) | 2·45 | ||||
| Ratio of uric acid, for example, is arrived at thus |
| = 2·33 | |||
The results which we obtained are given in the following table:—
Effects of Guaiacum Resin on the Urine of a Normal Individual.
| Date. | Sp. Gr. | Urea. | Uric Acid. | Hippuric Acid. | “R.U.A.” | “R.H.A.” | |
|---|---|---|---|---|---|---|---|
| With guaiacum | 28/12/11 | 1·0107 | 2·29 | 0·09 | 0·09 | 4·43 | 4·34 |
| With guaiacum | 29/12/11 | 1·0247 | 1·29 | 0·08 | 0·1 | 3·34 | 4·04 |
| With guaiacum | 1/1/12 | 1·0215 | 2·56 | 0·015 | 0·15 | 4·88 | 6·97 |
| With guaiacum | 2/1/12 | 1·0141 | 2·82 | 0·10 | 0·2 | 4·2 | 8·20 |
| Without guaiacum | 4/1/12 | 1·0229 | 2·42 | 0·06 | 0·1 | 2·62 | 4·36 |
| Without guaiacum | 5/1/12 | 1·0249 | 2·42 | 0·08 | 0·2 | 3·16 | 8·03 |
| Without guaiacum | 8/1/12 | 1·0255 | 3·09 | 0·10 | 0·225 | 4·11 | 8·12 |
| With guaiacum | 11/1/12 | 1·0233 | 2·56 | 0·09 | 0·1 | 3·7 | 4·29 |
| With guaiacum | 12/1/12 | 1·0213 | 1·88 | 0·075 | 0·1 | 3·05 | 4·69 |
| Without guaiacum | 24/1/12 | 1·0239 | 2·42 | 0·08 | 0·038 | 3·45 | 1·57 |
| Without guaiacum | 25/1/12 | 1·0229 | 2·15 | 0·06 | 0·05 | 2·61 | 2·18 |
| Average uric acid ratio under guaiacum resin | = | 3·39 |
| Average uric acid ratio without guaiacum resin | = | 3·19 |
| Average hippuric acid ratio under guaiacum resin | = | 5·43 |
| Average hippuric acid ratio without guaiacum resin | = | 4·49 |
The quantity of hippuric acid normally found is known to vary enormously, e.g., between 0·02 and 0·25 per cent. From this we deduced, for purpose of this investigation, a mean normal R.H.A. of 7·3. A number of other investigations were conducted on analogous lines, but need not be recorded.
From the results of these experiments one notices an average increase of uric and hippuric acids during the “+ guaiacum” periods. It is not possible to draw a conclusion without further corroboration. The amount of each acid from day to day is seen to be erratic, and the process of estimation of hippuric acid is not accurate.
[63] “Weakly mineralised thermal muriated waters, such as those of Baden-Baden in Germany, and Bourbon-Lancy in France, which in character and action approach the simple thermal group, may also show great radio-activity. In fact, the Büttquelle of Baden-Baden in this respect rivals some of the most radio-active springs of Gastein. Of Bourbon-Lancy springs, according to A. Piatot, the least mineralised are the most radio-active.”—“Climato-therapy and Balneo-therapy,” by Sir Hermann Weber.
Sir William Ramsay’s Analysis of the Bath Waters.