That it was his pituitary which first failed him, rather than the thyroid or adrenal, which might have, is demonstrated by a number of considerations. Before he made himself Emperor, it was noticed that he was becoming fat, a pituitary symptom. A comparison of portraits at different stages of his rise and fall shows an increasing abdominal paunch, and a laying down of fat in the pituitary areas, around the hips, the legs and so on. The beginning of weakness in judgment that he was to exhibit soon in the invasion of Russia manifested itself at the same time. His keen calculating ability attained the peak of its curve at Austerlitz, Jena and Friedland. Thereafter, the descent begins. A rash, grandiose, speculative quality enters his projects, and divorces the elaborate coordination of means and end from his plans. That his thyroid energy capacity did not fail him is indicated by the fact that at St. Albans he would ride for three hours at the end of the day to tire himself sufficiently for sleep. That his adrenals were not affected is indicated by the brutality which remained characteristic to the end of his life.

The findings after death confirm the view of him as an unstable pituitocentric who succumbed to pituitary insufficiency toward the latter half of his life. We possess the account of the postmortem by Dr. Henry, who performed it. "The whole surface of the body was deeply covered with fat. Over the sternum, where generally the bone is very superficial, the fat was upwards of an inch deep, and an inch and a half or two inches on the abdomen. There was scarcely any hair on the body, and that of the head was thin, fine and silky. The whole genital system (very small) seemed to exhibit a physical cause for the absence of sexual desire, and the chastity which had been stated to have characterized the deceased (during his stay at St. Helena). The skin was noticed to be very white and delicate as were the hands and arms. Indeed the whole body was slender and effeminate. The pubis much resembled the Mons Veneris in women. The muscles of the chest were small, the shoulders were narrow and the hips wide." In other words, the typical feminization of the body which accompanies pituitary insufficiency was found. He died of a cancer of the stomach. But before his death there were noted the mental transformations that succeed deficiency of his central endocrine. Apathy, indolence, fatigability, and frilosity were what impressed his associates at St. Helena. The deterioration of his mentality was also exemplified in his literary diversions, the "Siege of Troy" and the "Essay on Suicide." The puerility of these productions, as well as of his conduct, a sulking before his captors, and the decline of his physical energy, once a bottomless well, all point to the same conclusion.

The rise and fall of Napoleon followed the rise and fall of his pituitary gland. No better illustration exists of the fundamental determination of a personality and its career by an endocrine, aside from other factors of education, environment, accident and opportunity. Without the sort of endocrine equipment he was born with, however, none of the other factors would have found the material to work upon. Born, say, with more of a posterior pituitary than he had, which would have rendered him more sensitive to the sufferings of his fellow-creatures, if nothing else, and the forces of the Revolution probably would have swamped him from the very first moment of his emergence at Toulon, when the whiff of grape-shot, symptom of an inexorable, merciless intellect and will, started him upon the road that led to the Napoleonic Era. Destiny is always ironic. For the deficiency of the internal secretions which made him eligible for glory was responsible as well as for his downfall.

EPILEPSY AND MIGRAINE IN GENIUS

In the annals of genius, there occur a number of instances of those who suffered from attacks that have been diagnosed epilepsy or migraine. Because their ailment was associated with their extraordinary ability, they attracted an attention that concerned itself not at all with the circumstance that genius has also been liable to measles, scarlet fever, and so on. Epilepsy and migraine certainly occur in people of no supernormal gifts, and often in degenerates and subnormals. Yet the fact remains that these affections of the nervous system, so terrible to feel and to behold, have afflicted the finest brains of the race.

About forty years ago the idea established itself that epilepsy, exhibiting itself in one form or another as "fits," and migraine, the severe periodic sick headache, were interconvertible manifestations of the same underlying morbid process in the brain. Nothing in the way of a concrete cause, attackable on the material side, was elicited by this generalization. Then the investigations of the pituitary in the last decade produced evidence of epilepsy-like and migraine-like symptoms in sufferers from tumors or other enlargements of it. Reasoning back, cases of epilepsy and migraine began to be examined for evidences of involvement of the pituitary in their troubles. These accumulated rapidly. The physiognomy and physique of the pituito-centric were discovered in them. The phenomena noted in Napoleon's case were often present: lowering of the pulse, chilliness, and an increased irritability of the bladder. In women the attack often coincides with the menstrual period, a typical time of endocrine unbalance. Finally X-ray examinations of the sella turcica, the bony lodging of the pituitary, clinched the matter: it often appeared small, or enlarged, with erosions of the bone, signifying a desperate attempt of the gland to grow, and meet the needs of the organism. The complex of appearances called migraine now becomes understandable. There are a number of factors, such as fatigue, intense cold, or high sugar food like chocolate, which will cause an engorgement of the gland with blood and swelling of it. But they do not concern us now. Intense mental occupation, concentration as the popular term has it, acts as a patent excitor of the attack.

Brain work drives more blood into the brain and the gland. Besides, mental activity is accompanied by increased function of the ante-pituitary, if intellectual, or of the post-pituitary if emotional. Brain work then causes a temporary enlargement of the gland. If, now, the bone container of the endocrine is too small to permit of much swelling, the bone will be pressed against or even worn into. This means headache, severe, easily going on to the kind known as sick-headache. The nerves which move the eyes in various directions lie next to the pituitary. If, in its expansion, it moves sufficiently outward, it may press upon, irritate them or paralyze, and so evolve various eye disturbances in association with the headache. No one can overrate this conception of migraine, for a number of men of genius have suffered from sick-headache and eye symptoms.

As for epilepsy, the problem is more complex. One has to rule out first those who have organic destructive disease of the brain. But they are out of our field: genius predicates at least an intact brain. Of the others a number may be interpreted upon an endocrine basis. At least they will, in their physiognomy, physique, mentality, conduct and character, document the glandular constellation under which they live, and a proper understanding of which is necessary for them to be helped. One frequently seen is the thymo-centric, with small enclosed sella turcica. The latter fact explains the occurrence of the epilepsy. Periodic variations in the secretory tides of the other endocrines, the ovaries, the thyroid, and so on, may determine the onset of the attack of "fits." The point is that when epilepsy plays a constant part in the life history of a man of genius, we are justified in assuming a disturbed balance among his hormones, and so a reasoned picture perhaps of the foundations for the erratic in his behaviour or his productions.

THE NEURASTHENIC GENIUS

The fin de siècle intelligentsia of the nineteenth century were quite stirred up by a publication of Max Nordau on "Degeneration," in which a number of revered artists and intelligents were held up to public scorn as degenerates and neurasthenics. So wrought up were they, in fact, that Bernard Shaw was moved to compose a defense entitled "The Sanity of Art." In spite of the Great Vegetarian's dialectics, it remains to be explained why a certain species of creative ability has been combined with the fatigability, variability and general wretched irritability of every organ and tissue in the body which taught them that they were sensitive souls imprisoned in the flesh. Going from doctor to doctor as from pillar to post, from this medical creed to that hygienic cult, lucky to escape the worst, often landing upon the bosom of New Thought for succor. We have noted in previous chapters the relation of neurasthenia to the glands of internal secretion in general, and to adrenal insufficiency in particular. A closer examination of neurasthenic genius will show it to consist essentially of a pituitocentric in whom for one reason or another, congenital (the persistence of the thymus) or acquired (shocks, accidents, diseases) there has been failure of the adrenals, thyroid or the interstitial cells, about in the order of their occurrence.