During the first period of three years, while the brain is increasing notably and rapidly in volume, the cranium undergoes various and interesting transformations. The pentagonal form of the cranium tends steadily to become rounder, because the primitive nodules are diminishing, or even disappear, although in this regard many individual varieties result; and the processes of ossification reach their completion. This is the most important period of growth, during which the individual development of the perfect cranial form may be attained, provided the rhythm of growth between the brain and its envelope remains harmonious; or again, certain deformations may be definitely established, owing to the intervention of some pathological condition or a disturbance of nutrition, altering either the internal volume or the normal process of ossification of the bony covering.
The first closing of the fontanelles takes place, in our race, in those of the asterion (posterior to the temporal bones), and next in those of the pterion; and it sometimes happens, as an anomaly of growth that leaves no external trace in the living man, that a little bone is formed, duplicating the shape of the fontanelle itself; such little bones, very common in abnormal crania, are called Wormian bones. They may occur in connection with any of the fontanelles, but especially with that of the bregma.
Fig. 56.—Cranium of adult with abnormal medio-frontal suture.
The fontanelle of the lambda generally closes during the first year; and the last of all the fontanelles to close is the largest, which is situated toward the front of the head, at the bregma, and is well known, even by the common people, and can easily be felt upon a child's head; it generally closes toward the end of the second year; and its characteristics may furnish valuable indications of abnormality or insufficiency of the child's development. For example, if it diminishes and disappears ahead of time, this may constitute the first symptom of microcephaly, or at all events, of submicrocephaly (i.e., a case of microcephaly that is not very pronounced). On the contrary, when this fontanelle remains dilated and delays its normal closing, this is a sign of organic weakness and debilitating disease (cachexia, rickets, myxedema). Furthermore, the fontanelle in question may alter its characteristic appearance in certain forms of sickness. In the case of hydrocephaly it becomes distended, while in enteritis, on the contrary, in which the organism parts with a large proportion of liquid, it becomes depressed.
The sutures also undergo notable changes during this period of life. The first to become effaced is the metopic or medio-frontal suture, which is destined to close and form a single bone; by the end of the first year it is obliterated throughout the middle third of its length, and thereafter the process of suturation spreads upward and downward until it is completed at the end of the second year (Welcker, Haeckel, Humphry). Sometimes, however, this suture is not obliterated until very late, and there are anomalous cases where it has remained throughout life, giving the forehead a characteristic form (pronounced frontal nodules and a slight palpable furrow along the medial line of the forehead).
During this same time a fusion has also taken place between the occipital squama and the two lateral or condyloid portions; but the resultant whole still remains separated from the corpus or base of the occipital bone, which will not become welded into one solid piece with the rest before the age of seven years.
At the age of three, the ossification of the cranial vault has been completed. In place of being depressed and protuberant, as it was at birth, the cranium has grown upward and forward in the frontal region, assuming an almost definitive form; the volume of the cranium has at the same time undergone an exceedingly rapid growth, attaining proportions very near to those of an adult.
From the age of three onward the head grows slowly, and its transformations are much slighter and fewer. The cranial capacity which at birth is 415 cubic centimetres, becomes at the age of three, 1,200, at the age of fifteen, 1,393, and in the adult, 1,400 cu. cm. respectively. Accordingly we might say that at the age of three a sort of repose has been established in the growth both of the the brain and of the cranium; this is the age at which an awakening begins in the child of that intelligence which is to put him in touch with the external world, and it is also the age at which he may begin his education in school.
Third Period.—There follows a slow and parallel growth of both brain and cranium. The ossification of the cranium itself reaches completion. At the age of seven the occipital is definitely solidified into a single bone and between the years of fifteen and twenty the body of the sphenoid also becomes welded to the occiput. This process of synostosis begins from the interior of the cranium, and only subsequently manifests itself externally. Consequently, the basilar suture closes at the time when the last large molars, the so-called "wisdom teeth," appear. After this period, the base of the cranium can no longer undergo any sort of growth, and in the case of uneducated persons the complete development of the cranium is definitely accomplished.