Laveran had found that in the blood of sufferers who recover spontaneously from malarial fever there are a great number of corpuscles which have no longer the rounded forms of the plasmodia, but are crescent-shaped and rayed. He took these to be transformations of the plasmodia, "modified in form" and "incapable of producing disease," and pronounced them to be "degenerate" organisms, almost as if they had been deformed and exhausted by the "excess of work" they had previously performed. These organisms were described as "Laveran's degenerative forms." After the discovery of the transmission of malaria in 1900, Laveran's "degenerative forms" were recognized as the sexual individuals of the reproductive cycle: individuals which were incapable of conjugation in the blood of man, and could only produce new organisms in the body of the mosquito. We may well wonder: Why did not Laveran simply recognize those sexual forms, and why did he not seek for the period of conjugation in the plasmodia, which were animal micro-organisms? If he had borne in mind the complete cycle of the protozoa, he would have recognized them. But evidently Morel's theories of the degeneration of man had made a much livelier impression on his imagination; and his leap from these remote theories to his interpretation of the plasmodia seemed an achievement of "genius." It may be said that this "feat of genius," this visionary generalization, prevented Laveran from seeing the truth. A form of arrogance and levity is apparent in such errors.
Moreover, we are astonished by something still more serious: how came it that hundreds and thousands of students throughout the world accepted Laveran's error with their eyes shut, that not one among so many took into consideration on his own account the cycle of the protozoa, and that not one was sufficiently independent to set about studying the phenomenon for himself? What is this mental form of inertia? and why does it produce itself in man? All these disciples, heedless of the problem presented to their minds by the sexual form of the plasmodium, left it alone, although it had not yet been solved, and certainly had no intuition of the fame, the progress in science, and the benefit to humanity which would have been the outcome, had the problem constituted an obstacle which had arrested their attention, saying: "Solve me."
They passed on indifferently, commending Laveran's "effort of genius," repeating with him: They are degenerate forms. A futile effort, which only increased a crowd of persons who had resigned their own individuality all unconsciously.
Another biological acquisition was the assurance that the circulatory system of the blood is a closed system of vessels, and that the enclosing epithelium is not permeable by non-incisive solid bodies such as vegetable microbes, and still less by rounded protozoa, which are much larger than microbes and soft in substance. This well-known and clearly demonstrated fact ought to have suggested a problem to the minds of students: How do the protozoa of malaria enter the circulatory current of the blood? But ever since the days of Hippocrates, Pliny, Celsius and Galen it had been held that this fever was caused by the "poisonous atmosphere" of marsh lands, the bad air of the morning and the evening, so much so that even a few years before the discovery of the real cause of malaria, eucalyptus trees were planted in the belief that they would filter and disinfect the air. How was it that no one asked himself how it was possible that the plasmodia could enter the current of the blood from the air? What was the species of torpor which took possession of the intelligence of persons who had specialized in intellectual work? Here was a colossal sum of intelligence, without any individuality.
Until Ross discovered that birds are inoculated with malaria by a particular kind of mosquito.
And then, behold! we have at last the fundamental argument from which the knowledge of the truth sprang forth: "If birds are inoculated with malaria by mosquitoes, then the same thing must happen to man."
A simple argument, which sped like an arrow to the final discovery. Nothing seemed more incredible than the fact that in the malarial regions good air and fertile soil were to be found, that it was possible to breathe that air morning and evening and remain in perfect health, so long as one was not bitten by mosquitoes, and that the innumerable peasants who were wasted by malarial anemia would be saved and restored if they protected themselves by mosquito-netting. But after the first stupefaction, when men were convinced of the facts, there was an outcry from all the intelligent: How was it possible that we did not find it out before? Was not the cycle of the protozoa a well-known fact? Did not every one declare that the system of circulation was closed and impervious to micro-organisms? Was it not natural to think that only a blood-sucking insect could innoculate it?
How many students felt that glory had passed close to them, and were amazed and saddened by the knowledge, like the disciples of Emmäus, who said to each other when the Master disappeared before they recognized Him: "Did not our hearts burn within us when He spoke and expounded the Scriptures to us?"
Many must have thought: We worked so laboriously only to encumber our minds, and yet but one thing was needful: we should have been humble and simple, but independent. Instead, we filled our souls with darkness, and the ray that would have made us see, could not penetrate to us.
Let us take some grosser errors. As far back as the days of the Greek civilization it was known empirically that "stones can fall from the sky." Falls of aërolites are recorded in the most ancient Chinese chronicles. In the Middle Ages and in modern times intimations of the fall of aërolites have increased in frequency. Remarkable facts are indeed recorded in history in connection with similar phenomena: the meteorite which fell in 1492 served the Emperor Maximilian I of Germany as a pretext to excite Christendom to a war against the Turks. Nevertheless, the phenomenon was not admitted by men of science until the eighteenth century. One of the largest meteorites on record was that which fell near Agram in 1751; it weighed about forty kilogrammes, and was deposited and catalogued in the court mineralogical museum at Vienna. This is what Stütz, a German savant, had to say on the subject in 1790: "Those ignorant of natural history may believe that iron has fallen from the sky, and even educated men in Germany may have believed this in 1751, taking into account the universal ignorance then prevalent as to natural history and physics; but in our times it would be unpardonable to admit even the plausibility of such fables."