The Public Library of Science (PLoS) was founded in October 2000 by biomedical scientists Harold Varmus, Patrick Brown and Michael Eisen, from Stanford University, Palo Alto, and University of California, Berkeley. Headquartered in San Francisco, PLoS is a non-profit organization whose mission is to make the world’s scientific and medical literature a public resource in free online archives. Instead of information disseminated in millions of reports and thousands of online journals, a single point would give access to the full content of these articles, with a search engine and hyperlinks between articles.

PLoS posted an open letter requesting the articles presently published by journals to be distributed freely in online archives, and asking researchers to promote the publishers willing to support this project. From October 2000 to September 2002, the open letter was signed by 30,000 scientists from 180 countries. The publishers' answer was much less enthusiastic, although a number of publishers agreed for their articles to be distributed freely immediately after publication, or six months after publication in their journals. But even the publishers who initially agreed to support the project made so many objections that it was finally abandoned.

Another objective of PLoS was to become a publisher while creating a new model of online publishing based on free dissemination of knowledge. In early 2003, PLoS created a non- profit scientific and medical publishing venture to provide scientists and physicians with free high-quality, high-profile journals in which to publish their work. The journals were PLoS Biology (launched in 2003), PLoS Medicine (2004), PLoS Genetics (2005), PLoS Computational Biology (2005), PLoS Pathogens (2005), PLoS Clinical Trials (2006) and PLoS Neglected Tropical Diseases (2007), the first scientific journal on this topic.

All PLoS articles are freely available online, on the websites of PLoS and in the public archive PubMed Central, run by the National Library of Medicine. The articles can be freely redistributed and reused under a Creative Commons license, including for translations, as long as the author(s) and source are cited. PLoS also launched PLoS ONE, an online forum meant to publish articles on any subject relating to science or medicine.

Three years after the beginning of PLoS as a publisher, PLoS Biology and PLoS Medicine have had the same reputation for excellence as the leading journals Nature, Science and The New England Journal of Medicine. PLoS has received financial support from several foundations while developing a viable economic model from fees paid by published authors, advertising, sponsorship, and paid activities organized for PLoS members. PLoS also hopes to encourage other publishers to adopt the open access model, or to convert their existing journals to an open access model.

# Wikipedia

Wikipedia was launched in January 2001 by Jimmy Wales and Larry Sanger (Larry resigned later on). It has quickly grown into the largest reference website on the internet, financed by donations, with no advertising. Its multilingual content is free and written collaboratively by people worldwide, who contribute under a pseudonym. Its website is a wiki, which means that anyone can edit, correct and improve information throughout the encyclopedia. The articles stay the property of their authors, and can be freely used according to the GFDL (GNU Free Documentation License).

In December 2004, Wikipedia had 1.3 million articles (by 13,000 contributors) in 100 languages. In December 2006, it had 6 million articles in 250 languages. In May 2007, it had 7 million articles in 192 languages, including 1.8 million articles in English, 589,000 articles in German, 500,000 articles in French, 260,000 articles in Portuguese, and 236,000 articles in Spanish.

Wikipedia is hosted by the Wikimedia Foundation, founded in June 2003, which has run a number of other projects, beginning with Wiktionary (launched in December 2002) and Wikibooks (launched in June 2003), followed by Wikiquote, Wikisource (texts from public domain), Wikimedia Commons (multimedia), Wikispecies (animals and plants), Wikinews, Wikiversity (textbooks), and Wiki Search (search engine).

# Citizendium